Spleen Tyrosine Kinase Inhibitor TAK-659 Prevents Splenomegaly and Tumor Development in a Murine Model of Epstein-Barr Virus-Associated Lymphoma

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Spleen Tyrosine Kinase Inhibitor TAK-659 Prevents Splenomegaly and Tumor Development in a Murine Model of Epstein-Barr Virus-Associated Lymphoma

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article

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wetenschappelijk artikel

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наукова стаття, опублікована в серпні 2018

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Spleen Tyrosine Kinase Inhibit ...... Barr Virus-Associated Lymphoma

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Spleen Tyrosine Kinase Inhibit ...... Barr Virus-Associated Lymphoma

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Spleen Tyrosine Kinase Inhibit ...... Barr Virus-Associated Lymphoma

@en

Spleen Tyrosine Kinase Inhibit ...... Barr Virus-Associated Lymphoma

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Spleen Tyrosine Kinase Inhibit ...... Barr Virus-Associated Lymphoma

@en

Spleen Tyrosine Kinase Inhibit ...... Barr Virus-Associated Lymphoma

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P1476

Spleen Tyrosine Kinase Inhibit ...... Barr Virus-Associated Lymphoma

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P2093

Ali Ucur

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Duran Ustek

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Jessica Huck Sappal

http://www.w3.org/2001/XMLSchema#string

Jie Yu

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Karuppiah Kannan

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Mengkun Zhang

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Muzaffer Arikan

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Osman Cen

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Yeter Cen

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P2860

Identification of the WW domain-interaction sites in the unstructured N-terminal domain of EBV LMP 2A

Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinases

Epstein-Barr virus LMP2A-induced B-cell survival in two unique classes of EmuLMP2A transgenic mice

Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia

S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway

Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro

An open-label phase 2 trial of entospletinib (GS-9973), a selective spleen tyrosine kinase inhibitor, in chronic lymphocytic leukemia

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

The non-receptor tyrosine kinase Syk is a target of Cbl-mediated ubiquitylation upon B-cell receptor stimulation.

Syk tyrosine kinase required for mouse viability and B-cell development

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scholarly article

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10.1128/MSPHEREDIRECT.00378-18

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English

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P478

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Leo Gordon

Richard Longnecker

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2018-08-22T00:00:00Z

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30135222

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6106053

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