Living Neurons with Tau Filaments Aberrantly Expose Phosphatidylserine and Are Phagocytosed by Microglia

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Living Neurons with Tau Filaments Aberrantly Expose Phosphatidylserine and Are Phagocytosed by Microglia

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im August 2018 veröffentlichter wissenschaftlicher Artikel

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scientific article published on 01 August 2018

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wetenschappelijk artikel

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наукова стаття, опублікована в серпні 2018

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Living Neurons with Tau Filame ...... Are Phagocytosed by Microglia

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Living Neurons with Tau Filame ...... Are Phagocytosed by Microglia

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Living Neurons with Tau Filame ...... Are Phagocytosed by Microglia

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Living Neurons with Tau Filame ...... Are Phagocytosed by Microglia

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Living Neurons with Tau Filame ...... Are Phagocytosed by Microglia

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Living Neurons with Tau Filame ...... Are Phagocytosed by Microglia

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P1476

Living Neurons with Tau Filame ...... Are Phagocytosed by Microglia

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P2093

Aviva M Tolkovsky

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Bernardino Ghetti

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Maria Grazia Spillantini

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Michel Goedert

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P2860

Oxidatively modified phosphatidylserines on the surface of apoptotic cells are essential phagocytic 'eat-me' signals: cleavage and inhibition of phagocytosis by Lp-PLA2

Familial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filaments

Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain.

Both the apoptotic suicide pathway and phagocytosis are required for a programmed cell death in Caenorhabditis elegans.

Identification of a factor that links apoptotic cells to phagocytes

Lactadherin promotes VEGF-dependent neovascularization

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

Exposure of phosphatidylserine on the cell surface

Elimination of unfit cells maintains tissue health and prolongs lifespan

Inhibition of microglial phagocytosis is sufficient to prevent inflammatory neuronal death

P304

1939-1948.e4

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scholarly article

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10.1016/J.CELREP.2018.07.072

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English

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P478

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Jack H Brelstaff

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2018-08-01T00:00:00Z

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P698

30134156

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P921

microglia

P932

6161320

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