Akt and mTORC1 signaling as predictive biomarkers for the EGFR antibody nimotuzumab in glioblastoma

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Akt and mTORC1 signaling as predictive biomarkers for the EGFR antibody nimotuzumab in glioblastoma

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scientific article published on 21 August 2018

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wetenschappelijk artikel

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наукова стаття, опублікована в серпні 2018

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Akt and mTORC1 signaling as pr ...... dy nimotuzumab in glioblastoma

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Akt and mTORC1 signaling as pr ...... dy nimotuzumab in glioblastoma

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Akt and mTORC1 signaling as pr ...... dy nimotuzumab in glioblastoma

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Akt and mTORC1 signaling as pr ...... dy nimotuzumab in glioblastoma

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Akt and mTORC1 signaling as pr ...... dy nimotuzumab in glioblastoma

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Akt and mTORC1 signaling as pr ...... dy nimotuzumab in glioblastoma

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P1476

Akt and mTORC1 signaling as pr ...... dy nimotuzumab in glioblastoma

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Dirk Reuter

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Hans Urban

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Joachim P Steinbach

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Manfred Westphal

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Michel Mittelbronn

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Pia S Zeiner

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Torsten Pietsch

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P2860

Hallmarks of Cancer: The Next Generation

TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

Identification of a proline-rich Akt substrate as a 14-3-3 binding partner

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Regulation of mTORC1 by amino acids

Nimotuzumab, an antitumor antibody that targets the epidermal growth factor receptor, blocks ligand binding while permitting the active receptor conformation

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s40478-018-0583-4

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scholarly article

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10.1186/S40478-018-0583-4

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English

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P478

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Patrick N. Harter

Michael W Ronellenfitsch

Christian Senft

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2018-08-21T00:00:00Z

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1106281045

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30129426

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6102828

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