Bridging Cancer Biology with the Clinic: Comprehending and Exploiting IDH Gene Mutations in Gliomas

about

Bridging Cancer Biology with the Clinic: Comprehending and Exploiting IDH Gene Mutations in Gliomas

Item

http://www.wikidata.org/entity/Q58766030

description

article

@en

wetenschappelijk artikel

@nl

name

Bridging Cancer Biology with t ...... IDH Gene Mutations in Gliomas

@en

Bridging Cancer Biology with t ...... IDH Gene Mutations in Gliomas

@nl

type

Item

label

Bridging Cancer Biology with t ...... IDH Gene Mutations in Gliomas

@en

Bridging Cancer Biology with t ...... IDH Gene Mutations in Gliomas

@nl

prefLabel

Bridging Cancer Biology with t ...... IDH Gene Mutations in Gliomas

@en

Bridging Cancer Biology with t ...... IDH Gene Mutations in Gliomas

@nl

P1476

Bridging Cancer Biology with t ...... IDH Gene Mutations in Gliomas

@en

P2093

Ourania Romanidou

http://www.w3.org/2001/XMLSchema#string

Vassiliki Kotoula

http://www.w3.org/2001/XMLSchema#string

P2860

A sequence-specific, single-strand binding protein activates the far upstream element of c-myc and defines a new DNA-binding motif

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

An integrated genomic analysis of human glioblastoma multiforme

IDH1 and IDH2 mutations in gliomas

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas

IDH1/2 mutations target a key hallmark of cancer by deregulating cellular metabolism in glioma

P304

421-436

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.21873/CGP.20101

http://www.w3.org/2001/XMLSchema#string

P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

George Fountzilas

P698

30194083

http://www.w3.org/2001/XMLSchema#string

P921

cancer research

molecular biology

P932

6199574

http://www.w3.org/2001/XMLSchema#string