Smurfs in Protein Homeostasis, Signaling, and Cancer

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Smurfs in Protein Homeostasis, Signaling, and Cancer

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wetenschappelijk artikel

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наукова стаття, опублікована у 2018

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Smurfs in Protein Homeostasis, Signaling, and Cancer

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Smurfs in Protein Homeostasis, Signaling, and Cancer

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Smurfs in Protein Homeostasis, Signaling, and Cancer

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Smurfs in Protein Homeostasis, Signaling, and Cancer

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Smurfs in Protein Homeostasis, Signaling, and Cancer

@en

Smurfs in Protein Homeostasis, Signaling, and Cancer

@nl

P1476

Smurfs in Protein Homeostasis, Signaling, and Cancer

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P2093

Gal Levy-Cohen

http://www.w3.org/2001/XMLSchema#string

Michael Blank

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Praveen Koganti

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P2860

A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

Ablation of Smurf2 reveals an inhibition in TGF-β signalling through multiple mono-ubiquitination of Smad3

Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressor

Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins

Targeting EZH2 in cancer

Histone H2B monoubiquitination: roles to play in human malignancy

Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity

Regulation of cell polarity and protrusion formation by targeting RhoA for degradation

P304

295

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P31

scholarly article

P356

10.3389/FONC.2018.00295

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P407

English

P478

http://www.w3.org/2001/XMLSchema#string

P577

2018-01-01T00:00:00Z

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P698

30116722

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P921

cancer research

P932

6082930

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