A PDX1-ATF transcriptional complex governs β cell survival during stress

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A PDX1-ATF transcriptional complex governs β cell survival during stress

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scientific article published on 01 August 2018

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wetenschappelijk artikel

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наукова стаття, опублікована в листопаді 2018

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A PDX1-ATF transcriptional complex governs β cell survival during stress

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A PDX1-ATF transcriptional complex governs β cell survival during stress

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A PDX1-ATF transcriptional complex governs β cell survival during stress

@en

A PDX1-ATF transcriptional complex governs β cell survival during stress

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A PDX1-ATF transcriptional complex governs β cell survival during stress

@en

A PDX1-ATF transcriptional complex governs β cell survival during stress

@nl

P1476

A PDX1-ATF transcriptional complex governs β cell survival during stress

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P2093

Christine A Juliana

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Corey E Cannon

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Doris A Stoffers

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Juxiang Yang

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Matthew W Haemmerle

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P2860

TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death

BCL-2 is a downstream target of ATF5 that mediates the prosurvival function of ATF5 in a cell type-dependent manner

FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site

Increased islet apoptosis in Pdx1+/- mice

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Mammalian proapoptotic factor ChaC1 and its homologues function as γ-glutamyl cyclotransferases acting specifically on glutathione.

Perk is essential for translational regulation and cell survival during the unfolded protein response

Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

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39-48

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P31

scholarly article

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10.1016/J.MOLMET.2018.07.007

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English

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Austin L Good

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2018-08-01T00:00:00Z

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30174228

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P921

molecular biology

P932

6197747

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