An Essential Role of the Nuclear Factor of Activated T Cells in the Regulation of the Expression of the Cyclooxygenase-2 Gene in Human T Lymphocytes
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Human VRK2 (vaccinia-related kinase 2) modulates tumor cell invasion by hyperactivation of NFAT1 and expression of cyclooxygenase-2Cell proliferation depends on mitochondrial Ca2+ uptake: inhibition by salicylateAdditive effect of ethanol and HCV subgenomic replicon expression on COX-2 protein levels and activityActivation of interleukin-32 pro-inflammatory pathway in response to influenza A virus infectionHerpesviral G protein-coupled receptors activate NFAT to induce tumor formation via inhibiting the SERCA calcium ATPaseRenocortical mRNA expression of vasoactive factors during spironolactone protective effect in chronic cyclosporine nephrotoxicityPGE2 induces IL-6 in orbital fibroblasts through EP2 receptors and increased gene promoter activity: implications to thyroid-associated ophthalmopathy.Interferon-tau suppresses prostaglandin F2alpha secretion independently of the mitogen-activated protein kinase and nuclear factor kappa B pathways.Partners in transcription: NFAT and AP-1.Angiotensin II activates the calcineurin/NFAT signaling pathway and induces cyclooxygenase-2 expression in rat endometrial stromal cells.Trypanosoma cruzi infection and endothelin-1 cooperatively activate pathogenic inflammatory pathways in cardiomyocytes.NFAT1 is highly expressed in, and regulates the invasion of, glioblastoma multiforme cellsThe involvement of NFAT transcriptional activity suppression in SIRT1-mediated inhibition of COX-2 expression induced by PMA/Ionomycin.Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: roles of the nuclear factor of activated T cells and cyclooxygenase 2Cyclosporin A inhibits colon cancer cell growth independently of the calcineurin pathway.Depleting NFAT1 expression inhibits the ability of invasion and migration of human lung cancer cells.NFAT1 transcription factor regulates cell cycle progression and cyclin E expression in B lymphocytesTitanium particles stimulate COX-2 expression in synovial fibroblasts through an oxidative stress-induced, calpain-dependent, NF-kappaB pathwayCot kinase induces cyclooxygenase-2 expression in T cells through activation of the nuclear factor of activated T cells.Toll-like receptor 2 and mitogen- and stress-activated kinase 1 are effectors of Mycobacterium avium-induced cyclooxygenase-2 expression in macrophages.c-Rel is a critical mediator of NF-κB-dependent TRAIL resistance of pancreatic cancer cells.FAT1 acts as an upstream regulator of oncogenic and inflammatory pathways, via PDCD4, in glioma cells.Molecular targets of the antiinflammatory Harpagophytum procumbens (devil's claw): inhibition of TNFα and COX-2 gene expression by preventing activation of AP-1.NFAT signalling is a novel target of oncogenic BRAF in metastatic melanoma.Acetylsalicylic acid inhibits hepatitis C virus RNA and protein expression through cyclooxygenase 2 signaling pathways.Cyclooxygenase-2 induction by arsenite is through a nuclear factor of activated T-cell-dependent pathway and plays an antiapoptotic role in Beas-2B cells.The viral protein A238L inhibits cyclooxygenase-2 expression through a nuclear factor of activated T cell-dependent transactivation pathway.Treatment of human T cells with bisperoxovanadium phosphotyrosyl phosphatase inhibitors leads to activation of cyclooxygenase-2 gene.Inhibition of proliferation of gastric epithelial cells by a cyclooxygenase 2 inhibitor, JTE522, is also mediated by a PGE2-independent pathway.COX-2/PGE2: molecular ambassadors of Kaposi's sarcoma-associated herpes virus oncoprotein-v-FLIP.Transcriptional regulation of the c-Myc promoter by NFAT1 involves negative and positive NFAT-responsive elements.Activation of monocyte cyclooxygenase-2 gene expression by human herpesvirus 6. Role for cyclic AMP-responsive element-binding protein and activator protein-1.Failure of cyclosporin A to induce transforming growth factor beta (TGF-beta) synthesis in activated peripheral blood lymphocytes.Mechanistic study of saikosaponin-d (Ssd) on suppression of murine T lymphocyte activation.Annonaceae: Breaking the Wall of Inflammation.Screening new drugs for immunotoxic potential: III. assessment of the effects of selective and nonselective COX-2 inhibitors on T-cell-dependent antibody and natural killer cell responses in the rat.NFAT regulation of cystathionine γ-lyase expression in endothelial cells is impaired in rats exposed to intermittent hypoxia.Requirement of phospholipase C-gamma2 (PLCgamma2) for Dectin-1-induced antigen presentation and induction of TH1/TH17 polarization.Calcineurin inhibitor cyclosporine A activates renal Na-K-Cl cotransporters via local and systemic mechanisms.Neurotrophin activation of NFAT-dependent transcription contributes to the regulation of pro-nociceptive genes.
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An Essential Role of the Nuclear Factor of Activated T Cells in the Regulation of the Expression of the Cyclooxygenase-2 Gene in Human T Lymphocytes
description
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
im August 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published in Journal of Biological Chemistry
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в травні 2000
@uk
name
An Essential Role of the Nucle ...... -2 Gene in Human T Lymphocytes
@en
An Essential Role of the Nucle ...... -2 Gene in Human T Lymphocytes
@nl
type
label
An Essential Role of the Nucle ...... -2 Gene in Human T Lymphocytes
@en
An Essential Role of the Nucle ...... -2 Gene in Human T Lymphocytes
@nl
prefLabel
An Essential Role of the Nucle ...... -2 Gene in Human T Lymphocytes
@en
An Essential Role of the Nucle ...... -2 Gene in Human T Lymphocytes
@nl
P2093
P356
P1476
An essential role of the nucle ...... -2 gene in human T lymphocytes
@en
P2093
Martinez-Martinez S
P304
23627-23635
P356
10.1074/JBC.M001381200
P407
P577
2000-08-01T00:00:00Z