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p38 mitogen-activated protein kinase determines the susceptibility to cigarette smoke-induced emphysema in mice.Dual effect of neutrophils on pIgR/secretory component in human bronchial epithelial cells: role of TGF-betaComparison of the anti-inflammatory effects of Cilomilast, Budesonide and a p38 Mitogen activated protein kinase inhibitor in COPD lung tissue macrophages.Evaluation of glucocorticoid receptor function in COPD lung macrophages using beclomethasone-17-monopropionate.Novel function for the p38-MK2 signaling pathway in circulating CD1c+ (BDCA-1+) myeloid dendritic cells from healthy donors and advanced cancer patients; inhibition of p38 enhances IL-12 whilst suppressing IL-10.Epithelial cell senescence impairs repair process and exacerbates inflammation after airway injury.Oral and inhaled p38 MAPK inhibitors: effects on inhaled LPS challenge in healthy subjects.Murine cytomegalovirus (MCMV) infection upregulates P38 MAP kinase in aortas of Apo E KO mice: a molecular mechanism for MCMV-induced acceleration of atherosclerosis.Differential Effects of p38, MAPK, PI3K or Rho Kinase Inhibitors on Bacterial Phagocytosis and Efferocytosis by Macrophages in COPD.Population PK-PD Model for Tolerance Evaluation to the p38 MAP Kinase Inhibitor BCT197.Cutting Edge: CLEC5A Mediates Macrophage Function and Chronic Obstructive Pulmonary Disease PathologiesElectronic cigarette exposure triggers neutrophil inflammatory responses.Blood fibrinogen as a biomarker of chronic obstructive pulmonary diseaseRole of IL-18 in second-hand smoke-induced emphysemaElastase induced lung epithelial cell apoptosis and emphysema through placenta growth factor.Treating patients with respiratory disease who smoke.Therapeutic perspectives in bronchial vascular remodeling in COPD.Update in chronic obstructive pulmonary disease 2008.Silymarin attenuates cigarette smoke extract-induced inflammation via simultaneous inhibition of autophagy and ERK/p38 MAPK pathway in human bronchial epithelial cells.The cytokine network in chronic obstructive pulmonary disease.What's new in atopic eczema?What is the potential for inhaled p38 inhibitors in the treatment of chronic obstructive pulmonary disease?Emerging drugs for chronic obstructive pulmonary disease.Corticosteroid resistance and novel anti-inflammatory therapies in chronic obstructive pulmonary disease: current evidence and future direction.New anti-inflammatory targets for chronic obstructive pulmonary disease.Beneficial role of vitamin D3 in the prevention of certain respiratory diseases.Neutrophils and emerging targets for treatment in chronic obstructive pulmonary disease.Therapeutic potential of p38 MAP kinase inhibition in the management of cardiovascular disease.Investigational p38 inhibitors for the treatment of chronic obstructive pulmonary disease.Roles of p38α mitogen-activated protein kinase in mouse models of inflammatory diseases and cancer.An increased ratio of serum miR-21 to miR-181a levels is associated with the early pathogenic process of chronic obstructive pulmonary disease in asymptomatic heavy smokers.Pharmacological basis and scientific rationale underlying the targeted use of inhaled corticosteroid/long-acting β2-adrenergic agonist combinations in chronic obstructive pulmonary disease treatment.Secondhand Smoke-Prevalent Polycyclic Aromatic Hydrocarbon Binary Mixture-Induced Specific Mitogenic and Pro-inflammatory Cell Signaling Events in Lung Epithelial Cells.Transcriptional and posttranscriptional regulation of CXCL8/IL-8 gene expression induced by connective tissue growth factor.Kinases as Novel Therapeutic Targets in Asthma and Chronic Obstructive Pulmonary Disease.Genes and pathways underlying susceptibility to impaired lung function in the context of environmental tobacco smoke exposure.Aryl hydrocarbon receptor (AhR) attenuation of subchronic cigarette smoke-induced pulmonary neutrophilia is associated with retention of nuclear RelB and suppression of intercellular adhesion molecule-1 (ICAM-1).Pathogenesis of COPD and Asthma.The role of MAPK and Nrf2 pathways in ketanserin-elicited attenuation of cigarette smoke-induced IL-8 production in human bronchial epithelial cells.Role and regulation of MKP-1 in airway inflammation.
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P2860
description
im Januar 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published on 24 October 2007
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в січні 2008
@uk
name
Increased activation of p38 MAPK in COPD
@en
Increased activation of p38 MAPK in COPD
@nl
type
label
Increased activation of p38 MAPK in COPD
@en
Increased activation of p38 MAPK in COPD
@nl
prefLabel
Increased activation of p38 MAPK in COPD
@en
Increased activation of p38 MAPK in COPD
@nl
P2093
P50
P1476
Increased activation of p38 MAPK in COPD
@en
P2093
P356
10.1183/09031936.00036707
P50
P577
2007-10-24T00:00:00Z