about
Identification and characterization of kava-derived compounds mediating TNF-alpha suppression.In silico identification of an aryl hydrocarbon receptor antagonist with biological activity in vitro and in vivo.Disruption of the Class IIa HDAC Corepressor Complex Increases Energy Expenditure and Lipid Oxidation.Pharmacological validation of Trypanosoma brucei phosphodiesterases B1 and B2 as druggable targets for African sleeping sickness.Synthesis of Norbornane Bisether Antibiotics via Silver-mediated Alkylation.Luminescent probes for the bioimaging of small anionic species in vitro and in vivo.A fluorescent histone deacetylase (HDAC) inhibitor for cellular imaging.NMR studies of dextromethorphan in both isotropic and anisotropic states.An improved synthesis of 5'-fluoro-5'-deoxyadenosines.Modular synthesis of 4-aminocarbonyl substituted 1,8-naphthalimides and application in single molecule fluorescence detection.Blue Electrogenerated Chemiluminescence from Water-Soluble Iridium Complexes Containing Sulfonated Phenylpyridine or Tetraethylene Glycol Derivatized Triazolylpyridine Ligands.4-Hydroxy-N-propyl-1,8-naphthalimide esters: New fluorescence-based assay for analysing lipase and esterase activity.Synthesis and characterization of novel 2-amino-3-benzoylthiophene derivatives as biased allosteric agonists and modulators of the adenosine A(1) receptor.Synthesis and evaluation of cationic norbornanes as peptidomimetic antibacterial agentsNorbornane-based cationic antimicrobial peptidomimetics targeting the bacterial membraneAn expedient synthesis of N6-substituted-5'-modified adenosinesImproved synthesis and structural reassignment of MC1568: a class IIa selective HDAC inhibitorEvaluation of 4-Amino 2-Anilinoquinazolines against Plasmodium and Other Apicomplexan Parasites In Vitro and in a P. falciparum Humanized NOD-scid IL2Rγnull Mouse Model of MalariaHighly fluorescent and HDAC6 selective scriptaid analoguesMixed alkoxy/hydroxy 1,8-naphthalimides: expanded fluorescence colour palette and in vitro bioactivity
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P50
description
researcher ORCID ID = 0000-0002-6707-6064
@en
wetenschapper
@nl
name
Trent D Ashton
@ast
Trent D Ashton
@en
Trent D Ashton
@nl
type
label
Trent D Ashton
@ast
Trent D Ashton
@en
Trent D Ashton
@nl
prefLabel
Trent D Ashton
@ast
Trent D Ashton
@en
Trent D Ashton
@nl
P106
P31
P496
0000-0002-6707-6064