about
1,2,4-triazolo[1,5-a]quinoxaline derivatives and their simplified analogues as adenosine A₃ receptor antagonists. Synthesis, structure-affinity relationships and molecular modeling studies.Neuropeptide S receptor: recent updates on nonpeptide antagonist discovery.Medicinal chemistry of P2X receptors: agonists and orthosteric antagonists.Innovative functional cAMP assay for studying G protein-coupled receptors: application to the pharmacological characterization of GPR17.Simulation and Comparative Analysis of Different Binding Modes of Non-nucleoside Agonists at the A2A Adenosine Receptor.The Length and Flexibility of the 2-Substituent of 9-Ethyladenine Derivatives Modulate Affinity and Selectivity for the Human A2A Adenosine Receptor.A Novel Class of Dopamine D4 Receptor Ligands Bearing an Imidazoline Nucleus.Simulation and comparative analysis of binding modes of nucleoside and non-nucleoside agonists at the A2B adenosine receptorPurinergic P2X receptors: structural models and analysis of ligand-target interaction.Molecular modeling study on potent and selective adenosine A(3) receptor agonists.Different efficacy of adenosine and NECA derivatives at the human A3 adenosine receptor: insight into the receptor activation switch.Evaluation of adenine as scaffold for the development of novel P2X3 receptor antagonists.Antiproliferative evaluation of isofuranodiene on breast and prostate cancer cell lines.8-(2-Furyl)adenine derivatives as A₂A adenosine receptor ligands.Evidence for the existence of a specific g protein-coupled receptor activated by guanosineExploring the 7-oxo-thiazolo[5,4-d]pyrimidine core for the design of new human adenosine A3 receptor antagonists. Synthesis, molecular modeling studies and pharmacological evaluation
P50
Q35511885-FB1B0D1B-E36B-4DB6-8810-946C760228C6Q37859670-668738BF-68D3-48D3-AB26-8CE442A7C1B0Q38290903-E62AD5D5-9439-4BA0-B5B8-E0C84BB82CECQ39393180-4CEE1CA2-488A-466A-9E3D-4AE880ECA53FQ39469198-2BCBF9AA-4C2B-4E88-8EE4-4ED2163C5023Q39870318-1EBC6CDB-58BF-4D7E-B125-0E1B784A4095Q41444993-8F9E1CFB-733B-4E5F-9EF1-C031525017ADQ41692310-278890BA-AF3D-41A4-83F6-027CEAF737B3Q41740489-AEABED4D-A0E1-4496-A9E4-14EE253DCA2BQ42860062-7F199139-8D0B-4598-84C0-27CA3E74617EQ43988446-F25FF65A-5D38-4739-BDBE-AB304E77A652Q45331430-73866280-76EE-4004-AC5C-AD2EFA486352Q51747998-9A49F5C3-A8A4-4817-98C4-54028C076234Q51751278-580FA3C0-4B00-43F3-95EF-D26EDFFA2225Q83889177-C4849B64-F5BC-4B4A-8811-E157B52AA83AQ87116043-5E895768-BE63-40C8-8EA1-B8293FDE16C1
P50
description
onderzoeker
@nl
researcher ORCID ID = 0000-0003-1852-6716
@en
name
Ajiroghene Thomas
@ast
Ajiroghene Thomas
@en
Ajiroghene Thomas
@es
Ajiroghene Thomas
@nl
type
label
Ajiroghene Thomas
@ast
Ajiroghene Thomas
@en
Ajiroghene Thomas
@es
Ajiroghene Thomas
@nl
prefLabel
Ajiroghene Thomas
@ast
Ajiroghene Thomas
@en
Ajiroghene Thomas
@es
Ajiroghene Thomas
@nl
P106
P1153
37038620700
P31
P496
0000-0003-1852-6716