about
The NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells.HPV16 E7-dependent transformation activates NHE1 through a PKA-RhoA-induced inhibition of p38alpha.Protons extruded by NHE1: digestive or glue?FAD synthesis and degradation in the nucleus create a local flavin cofactor pool.Protease activity at invadopodial focal digestive areas is dependent on NHE1-driven acidic pHe.Protein kinase A gating of a pseudopodial-located RhoA/ROCK/p38/NHE1 signal module regulates invasion in breast cancer cell lines.Glucose increases extracellular [Ca2+] in rat insulinoma (INS-1E) pseudoislets as measured with Ca2+-sensitive microelectrodes.NHE1 promotes invadopodial ECM proteolysis through acidification of the peri-invadopodial space
P50
Q30479321-B563830E-7986-4F18-AFB0-5FD1A308E35CQ33379617-5FC37142-B988-4C53-B334-C7C48F65D31BQ37105130-8CF57F7C-4F45-4848-9277-D4AE6E9AC3B7Q37213905-023002F1-55BE-4201-8E22-05D104AE7B82Q39043494-06D63E76-9C82-4E9B-A437-4DB9200290B8Q40432766-50B3B5B5-01E7-4512-BD6C-2A7FFD125419Q46095528-6FE25D31-C98B-4D91-A2A4-A5C6CE620F9CQ61642117-57CF051E-A5DD-4C7F-AD83-2373D34963BE
P50
description
onderzoeker
@nl
researcher ORCID ID = 0000-0001-6859-9468
@en
name
Giovanni Busco
@ast
Giovanni Busco
@en
Giovanni Busco
@es
Giovanni Busco
@nl
type
label
Giovanni Busco
@ast
Giovanni Busco
@en
Giovanni Busco
@es
Giovanni Busco
@nl
prefLabel
Giovanni Busco
@ast
Giovanni Busco
@en
Giovanni Busco
@es
Giovanni Busco
@nl
P106
P1153
9844453800
P21
P31
P496
0000-0001-6859-9468
P569
1978-01-08T00:00:00Z