about
CDK4 is an essential insulin effector in adipocytesβ-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue.E2F1 inhibits circulating cholesterol clearance by regulating Pcsk9 expression in the liver.The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humansE2F1 mediates sustained lipogenesis and contributes to hepatic steatosis.Role of ChREBP in hepatic steatosis and insulin resistance.Carbohydrate responsive element binding protein and lipid homeostasis.Growth factor receptor binding protein 14 inhibition triggers insulin-induced mouse hepatocyte proliferation and is associated with hepatocellular carcinoma.KAT2B Is Required for Pancreatic Beta Cell Adaptation to Metabolic Stress by Controlling the Unfolded Protein Response.ChREBP, but not LXRs, is required for the induction of glucose-regulated genes in mouse liver.Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis.[The regulation of gene expression by glucose].E2F1, a Novel Regulator of Metabolism.CDK4 Phosphorylates AMPKα2 to Inhibit Its Activity and Repress Fatty Acid Oxidation.Chromatin immunoprecipitation improvements for the processing of small frozen pieces of adipose tissue.E2F1 promotes hepatic gluconeogenesis and contributes to hyperglycemia during diabetes.[Cell cycle regulators CDK4 and E2F1 control glucose and lipid homeostasis].T-cell factor 4 and β-catenin chromatin occupancies pattern zonal liver metabolism in miceHuman adipose tissue H3K4me3 histone mark in adipogenic, lipid metabolism and inflammatory genes is positively associated with BMI and HOMA-IR
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description
researcher ORCID ID = 0000-0003-3502-4814
@en
wetenschapper
@nl
name
Pierre-Damien Denechaud
@ast
Pierre-Damien Denechaud
@en
Pierre-Damien Denechaud
@es
Pierre-Damien Denechaud
@nl
type
label
Pierre-Damien Denechaud
@ast
Pierre-Damien Denechaud
@en
Pierre-Damien Denechaud
@es
Pierre-Damien Denechaud
@nl
prefLabel
Pierre-Damien Denechaud
@ast
Pierre-Damien Denechaud
@en
Pierre-Damien Denechaud
@es
Pierre-Damien Denechaud
@nl
P106
P1153
13405082000
P31
P496
0000-0003-3502-4814