A Microscopic View of the Store-Operated Calcium Entry-Pathway

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A Microscopic View of the Store-Operated Calcium Entry-Pathway

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wetenschappelijk artikel

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наукова стаття, опублікована у 2013

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A Microscopic View of the Store-Operated Calcium Entry-Pathway

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A Microscopic View of the Store-Operated Calcium Entry-Pathway

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A Microscopic View of the Store-Operated Calcium Entry-Pathway

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A Microscopic View of the Store-Operated Calcium Entry-Pathway

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A Microscopic View of the Store-Operated Calcium Entry-Pathway

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A Microscopic View of the Store-Operated Calcium Entry-Pathway

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P1476

A Microscopic View of the Store-Operated Calcium Entry-Pathway

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P2093

Jonathan Pacheco

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Luis Vaca

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P2860

STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation

Orai1 is an essential pore subunit of the CRAC channel

STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx

A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells

SARAF inactivates the store operated calcium entry machinery to prevent excess calcium refilling

STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1

CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry

Junctate is a Ca2+-sensing structural component of Orai1 and stromal interaction molecule 1 (STIM1)

STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

Modulation of STIM1 and capacitative Ca2+ entry by the endoplasmic reticulum luminal oxidoreductase ERp57

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1-13

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P31

scholarly article

P356

10.1155/2013/237192

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P478

2013

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P577

2013-01-01T00:00:00Z

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