Mechanism of parkin activation by PINK1 - Wikidata - awgldk - TriplyDB

Mechanism of parkin activation by PINK1

Mechanism of parkin activation by PINK1

http://www.wikidata.org/entity/Q59057919

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Mechanism of parkin activation by PINK1

http://www.wikidata.org/entity/Q59057919

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article publié dans la revue scientifique Nature

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scientific article published in Nature

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wetenschappelijk artikel

@nl

наукова стаття, опублікована в Nature в липні 2018

@uk

name

Mechanism of parkin activation by PINK1

@en

Mechanism of parkin activation by PINK1

@nl

type

label

Mechanism of parkin activation by PINK1

@en

Mechanism of parkin activation by PINK1

@nl

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Mechanism of parkin activation by PINK1

@en

Mechanism of parkin activation by PINK1

@nl

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Mechanism of parkin activation by PINK1

@en

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Christina Gladkova

http://www.w3.org/2001/XMLSchema#string

David Komander

http://www.w3.org/2001/XMLSchema#string

J Mark Skehel

http://www.w3.org/2001/XMLSchema#string

Sarah L Maslen

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P2860

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65

Ubiquitin is phosphorylated by PINK1 to activate parkin

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis

Structure of the human Parkin ligase domain in an autoinhibited state

Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases

Structure of parkin reveals mechanisms for ubiquitin ligase activation

Phasercrystallographic software

Features and development of Coot

Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation

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s41586-018-0224-x

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410-414

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scholarly article

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10.1038/S41586-018-0224-X

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2018-07-01T00:00:00Z

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