The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle
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Control of glycogen synthesis in cultured human muscle cellsHuman rsk isoforms: cloning and characterization of tissue-specific expressionAmino acid sequence of a novel protein phosphatase 1 binding protein (R5) which is related to the liver- and muscle-specific glycogen binding subunits of protein phosphatase 1Cloning of the complete coding region for human protein phosphatase inhibitor 2 using the two hybrid system and expression of inhibitor 2 in E. coliNeurabins recruit protein phosphatase-1 and inhibitor-2 to the actin cytoskeletonThe muscle-specific protein phosphatase PP1G/R(GL)(G(M))is essential for activation of glycogen synthase by exercisePhosphorylation and activation of human tyrosine hydroxylase in vitro by mitogen-activated protein (MAP) kinase and MAP-kinase-activated kinases 1 and 2Interaction of the ribosomal protein, L5, with protein phosphatase type 1Regulation and interaction of pp90(rsk) isoforms with mitogen-activated protein kinasesPositive and negative roles of p85 alpha and p85 beta regulatory subunits of phosphoinositide 3-kinase in insulin signalingPurification of the hepatic glycogen-associated form of protein phosphatase-1 by microcystin-Sepharose affinity chromatographyInhibitor-1 is not required for the activation of glycogen synthase by insulin in skeletal muscle.Insulin-stimulated phosphorylation of the protein phosphatase-1 striated muscle glycogen-targeting subunit and activation of glycogen synthase.Identification of protein phosphatase-1-binding proteins by microcystin-biotin affinity chromatography.Regulation of glycogen synthesis by amino acids in cultured human muscle cells.Effects of serine/threonine protein phosphatases on ion channels in excitable membranes.Pathogenesis of insulin resistance in skeletal muscle.GSK3beta: role in therapeutic landscape and development of modulators.Phosphorylation of the skeletal muscle glycogen-targetting subunit of protein phosphatase 1 in response to adrenaline in vivo.Identification of binding sites on protein targeting to glycogen for enzymes of glycogen metabolism.Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins.Rab4 is phosphorylated by the insulin-activated extracellular-signal-regulated kinase ERK1.The regulation of glycogen synthase by protein phosphatase 1 in 3T3-L1 adipocytes. Evidence for a potential role for DARPP-32 in insulin action.Expression profiling reveals altered satellite cell numbers and glycolytic enzyme transcription in nemaline myopathy muscle.The role of glycogen synthase kinase-3 in insulin resistance and type 2 diabetes.Regulation of glycogen synthase in skeletal muscle during exercise.The structure, role, and regulation of type 1 protein phosphatases.Insulin and Insulin-like Growth Factor 1 (IGF-1) Modulate Cytoplasmic Glucose and Glycogen Levels but Not Glucose Transport across the Membrane in Astrocytes.Testicular Metabolic Reprogramming in Neonatal Streptozotocin-Induced Type 2 Diabetic Rats Impairs Glycolytic Flux and Promotes Glycogen Synthesis.Genetics of type 2 diabetes mellitus: status and perspectives.Inhibition of GSK-3beta as a target for cardioprotection: the importance of timing, location, duration and degree of inhibition.The role of glycogen synthase in the development of hyperglycemia in type 2 diabetes: 'To store or not to store glucose, that's the question'.Increased mitochondrial calcium uniporter in adipocytes underlies mitochondrial alterations associated with insulin resistance.New emerging role of protein-tyrosine phosphatase 1B in the regulation of glycogen metabolism in basal and TNF-α-induced insulin-resistant conditions in an immortalised muscle cell line isolated from mice.The stress-activated protein kinases. A novel ERK subfamily responsive to cellular stress and inflammatory cytokines.Molecular aspects of non-insulin-dependent diabetes.Does mitogen-activated-protein kinase have a role in insulin action? The cases for and against.Epidermal growth factor receptor as a genetic therapy target for carcinoma cell radiosensitization.Inhibition of myogenesis by depletion of the glycogen-associated regulatory subunit of protein phosphatase-1 in rat skeletal muscle cells.Regulation of glucose transport and glycogen synthesis in L6 muscle cells during oxidative stress. Evidence for cross-talk between the insulin and SAPK2/p38 mitogen-activated protein kinase signaling pathways.
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P2860
The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle
description
article publié dans la revue scientifique Nature
@fr
scientific article published in Nature
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в Nature в листопаді 1990
@uk
name
The molecular mechanism by whi ...... s in mammalian skeletal muscle
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The molecular mechanism by whi ...... s in mammalian skeletal muscle
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type
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The molecular mechanism by whi ...... s in mammalian skeletal muscle
@en
The molecular mechanism by whi ...... s in mammalian skeletal muscle
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prefLabel
The molecular mechanism by whi ...... s in mammalian skeletal muscle
@en
The molecular mechanism by whi ...... s in mammalian skeletal muscle
@nl
P2093
P356
P1433
P1476
The molecular mechanism by whi ...... s in mammalian skeletal muscle
@en
P2093
P2888
P304
P356
10.1038/348302A0
P407
P577
1990-11-01T00:00:00Z
P6179
1038265672