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The Catalytic Architecture of Leukotriene C4 Synthase with Two Arginine ResiduesBronchial mast cells are the dominating LTC4S-expressing cells in aspirin-tolerant asthmaDetermination of structure and transcriptional regulation of CYSLTR1 and an association study with asthma and rhinitisThe mechanism of LTE4-induced histamine hyperresponsiveness in guinea-pig tracheal and human bronchial smooth muscle, in vitroAllergic asthmatics show divergent lipid mediator profiles from healthy controls both at baseline and following birch pollen provocationIdentification in mice of two isoforms of the cysteinyl leukotriene 1 receptor that result from alternative splicingCharacterization of mouse cysteinyl leukotriene receptors mCysLT1 and mCysLT2: differential pharmacological properties and tissue distributionRole of LTB₄ in the pathogenesis of elastase-induced murine pulmonary emphysemaSerine protease inhibitor attenuates ovalbumin induced inflammation in mouse model of allergic airway diseaseLeukotriene D4-induced activation of smooth-muscle cells from human bronchi is partly Ca2+-independent.Influence of leukotriene pathway polymorphisms on response to montelukast in asthma.Asthma and leukotrienes: antileukotrienes as novel anti-asthmatic drugs.Therapeutic advances: leukotriene antagonists for the treatment of asthma.Association of CACNG6 polymorphisms with aspirin-intolerance asthmatics in a Korean population.Randomized controlled trial of fish oil and montelukast and their combination on airway inflammation and hyperpnea-induced bronchoconstrictionDietary fatty acids and allergy.Corticosteroids and leukotrienes: chronobiology and chronotherapy.From bench to bedside. The hurdles of discovering a new leukotriene receptor antagonist.Pharmacological characterization of leukotriene receptors.The role of leukotrienes in the regulation of tone and responsiveness in isolated human airways.Role of eosinophil peroxidase in the origins of protein oxidation in asthma.Dimerization of human 5-lipoxygenase.Fatty acids and atopic disease.Montelukast during primary infection prevents airway hyperresponsiveness and inflammation after reinfection with respiratory syncytial virus.Biosynthesis of 5-oxo-6,8,11,14-eicosatetraenoic acid from 5-hydroperoxyeicosatetraenoic acid in the murine macrophage.Current treatment of asthma--focus on leukotrienes.Leukotriene inhibitors and non-steroidal therapies in the treatment of asthma.Detection of sputum eicosanoids in cystic fibrosis and in normal saliva by bioassay and radioimmunoassay.Oral nafazatrom in man: effect on inhaled antigen challengeAntileukotrienes in clinical development for asthma.Oxidative stress suppresses cysteinyl leukotriene generation by mouse bone marrow-derived mast cells.The leukotriene receptor antagonist zafirlukast inhibits sulfur dioxide-induced bronchoconstriction in patients with asthma.Allergens induce enhanced bronchoconstriction and leukotriene production in C5 deficient mice.Comparison of airway responses in sheep of different age in precision-cut lung slices (PCLS).The spontaneous electrical and mechanical activity of human bronchial smooth muscle: its modulation by drugs.Leukotriene receptor antagonists--risks and benefits for use in paediatric asthma.Interferon at the crossroads of allergy and viral infections.Role of leukotrienes in airway hyperresponsiveness in guinea-pigs.Inhibitory effects of MK-886 on arachidonic acid metabolism in human phagocytesEicosanoids and respiratory viral infection: coordinators of inflammation and potential therapeutic targets.
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P2860
description
article publié dans la revue scientifique Nature
@fr
scientific article published in Nature
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в Nature в грудні 1980
@uk
name
Leukotrienes are potent constrictors of human bronchi
@en
Leukotrienes are potent constrictors of human bronchi
@nl
type
label
Leukotrienes are potent constrictors of human bronchi
@en
Leukotrienes are potent constrictors of human bronchi
@nl
prefLabel
Leukotrienes are potent constrictors of human bronchi
@en
Leukotrienes are potent constrictors of human bronchi
@nl
P2093
P2860
P356
P1433
P1476
Leukotrienes are potent constrictors of human bronchi
@en
P2093
B Samuelsson
P Hedqvist
S E Dahlén
S Hammarström
P2860
P2888
P304
P356
10.1038/288484A0
P407
P577
1980-12-01T00:00:00Z
P6179
1043538501