Spondylometaphyseal dysplasia in mice carrying a dominant negative mutation in a matrix protein specific for cartilage-to-bone transition
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Genetic architecture of body size in mammalsGrowth defect in Grg5 null mice is associated with reduced Ihh signaling in growth platesRor2 knockout mouse as a model for the developmental pathology of autosomal recessive Robinow syndromeThe humerus of Eusthenopteron: a puzzling organization presaging the establishment of tetrapod limb bone marrowCollagens: building blocks at the end of the development line.Genetically altered mouse models: the good, the bad, and the ugly.Runx2 contributes to murine Col10a1 gene regulation through direct interaction with its cis-enhancerThe role of type X collagen in facilitating and regulating endochondral ossification of articular cartilage.Association of cartilage-specific deletion of peroxisome proliferator-activated receptor γ with abnormal endochondral ossification and impaired cartilage growth and development in a murine modelAbnormal compartmentalization of cartilage matrix components in mice lacking collagen X: implications for functionGrowth plate compressions and altered hematopoiesis in collagen X null mice.Establishment of a bone-specific col10a1:GFP transgenic zebrafish.Altered matrix at the chondro-osseous junction leads to defects in lymphopoiesis.Extracellular matrix and developing growth plate.Folding and assembly of type X collagen mutants that cause metaphyseal chondrodysplasia-type schmid. Evidence for co-assembly of the mutant and wild-type chains and binding to molecular chaperones.An essential role of discoidin domain receptor 2 (DDR2) in osteoblast differentiation and chondrocyte maturation via modulation of Runx2 activation.Stress relaxation of swine growth plate in semi-confined compression: depth dependent tissue deformational behavior versus extracellular matrix composition and collagen fiber organization.Type II collagen mutations in rare and common cartilage diseases.Raf signaling stimulates and represses the human collagen X promoter through distinguishable elements.Inhibition of terminal differentiation and matrix calcification in cultured avian growth plate chondrocytes by Rous sarcoma virus transformation.Characterization of human type X procollagen and its NC-1 domain expressed as recombinant proteins in HEK293 cells.Site-directed mutagenesis of human type X collagen. Expression of alpha1(X) NC1, NC2, and helical mutations in vitro and in transfected cells.Skeletal stiffening in an amphibious fish out of water is a response to increased body weight.In vitro modeling of matrix vesicle nucleation: synergistic stimulation of mineral formation by annexin A5 and phosphatidylserine.Metaphyseal chondrodysplasia type Schmid mutations are predicted to occur in two distinct three-dimensional clusters within type X collagen NC1 domains that retain the ability to trimerize.Type X collagen, a natural component of mouse articular cartilage: association with growth, aging, and osteoarthritis.Proximal DNA elements mediate repressor activity conferred by the distal portion of the chicken collagen X promoter.The role of type X collagen in endochondral ossification as deduced by Fourier transform infrared microscopy analysis.Active role of chondrocyte apoptosis in endochondral ossification.Multiple transcriptional elements in the avian type X collagen gene. Identification of Sp1 family proteins as regulators for high level expression in hypertrophic chondrocytes.Developmental pattern of expression of the mouse alpha 1 (XI) collagen gene (Col11a1).
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Spondylometaphyseal dysplasia in mice carrying a dominant negative mutation in a matrix protein specific for cartilage-to-bone transition
description
article publié dans la revue scientifique Nature
@fr
scientific article published in Nature
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wetenschappelijk artikel
@nl
наукова стаття, опублікована в Nature у вересні 1993
@uk
name
Spondylometaphyseal dysplasia ...... r cartilage-to-bone transition
@en
Spondylometaphyseal dysplasia ...... r cartilage-to-bone transition
@nl
type
label
Spondylometaphyseal dysplasia ...... r cartilage-to-bone transition
@en
Spondylometaphyseal dysplasia ...... r cartilage-to-bone transition
@nl
prefLabel
Spondylometaphyseal dysplasia ...... r cartilage-to-bone transition
@en
Spondylometaphyseal dysplasia ...... r cartilage-to-bone transition
@nl
P2093
P356
P1433
P1476
Spondylometaphyseal dysplasia ...... r cartilage-to-bone transition
@en
P2093
P2888
P356
10.1038/365056A0
P407
P577
1993-09-01T00:00:00Z
P6179
1020818456