Interleukin-1 receptor antagonist reduces mortality from endotoxin shock
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Refined crystal structure of the interleukin-1 receptor antagonist. Presence of a disulfide link and a cis-prolineTrial Watch-Immunostimulation with cytokines in cancer therapyCop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processingEarly immune responses accompanying human asymptomatic Ebola infectionsP-selectin and ICAM-1 mediate endotoxin-induced neutrophil recruitment and injury to the lung and liver.Interleukin-1 beta-specific partial agonists defined by site-directed mutagenesis studies.The role of phosphodiesterase 3 in endotoxin-induced acute kidney injury.Effect of tyrosine kinase inhibitors, imatinib and nilotinib, in murine lipopolysaccharide-induced acute lung injury during neutropenia recovery.Trial watch: Immunostimulatory cytokines in cancer therapy.Anti-inflammatory therapies in sepsis and septic shock.Physiological rationale for suppression of fever.Cytotoxic and non-cytotoxic roles of the CTL/NK protease granzyme B.Enhanced monocyte chemoattractant protein-1 production in aging mice exaggerates cardiac depression during endotoxemiaHeat shock proteins and cardiovascular pathophysiology.A glossary of circulating cytokines in chronic heart failure.Potential of anticytokine therapies in central nervous system ischaemia.Interleukin-1 receptor antagonist as therapy for inflammatory disorders.The effects of a selective inhibitor of c-Fos/activator protein-1 on endotoxin-induced acute kidney injury in mice.PPARγ signaling is required for mediating EETs protective effects in neonatal cardiomyocytes exposed to LPSDistinctive cytokines as biomarkers predicting fatal outcome of severe Staphylococcus aureus bacteremia in miceCytokine modulation in sepsis and septic shock.Anti-inflammatory strategies for the treatment of sepsis.Regulation of macrophage infiltration and activation in sites of chronic inflammation.Role of interleukin-1 in infectious diseases.Different role of cytokine mediators in septic shock related to meningococcal disease and surgery/polytrauma.Interleukin-1 in lipopolysaccharide induced chorioamnionitis in the fetal sheep.Transgenic mice expressing rabbit C-reactive protein are resistant to endotoxemia.Trial Watch: Immunostimulatory cytokines.Cytokines and cardiovascular disease.Trial Watch: Experimental Toll-like receptor agonists for cancer therapyCytokines and their interactions with other inflammatory mediators in the pathogenesis of sepsis and septic shock.Complexity of complement activation in sepsis.IL-1 mediates pulmonary and systemic inflammatory responses to chorioamnionitis induced by lipopolysaccharide.Sepsis: multiple abnormalities, heterogeneous responses, and evolving understanding.Noncoding RNAs and chronic inflammation: Micro-managing the fire within.Muramyldipeptide augments the actions of lipopolysaccharide in mice by stimulating macrophages to produce pro-IL-1β and by down-regulation of the suppressor of cytokine signaling 1 (SOCS1).Effects of the anti-sepsis drug, (S)-1-(α-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (CKD-712), on mortality, inflammation, and organ injuries in rodent sepsis models.Role of endogenous interleukin-1 receptor antagonist in regulating fever induced by localised inflammation in the rat.Is there a role for interleukin-1 blockade in intravenous immunoglobulin therapy?Pathobiology of lipopolysaccharide.
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Interleukin-1 receptor antagonist reduces mortality from endotoxin shock
description
article publié dans la revue scientifique Nature
@fr
scientific article published in Nature
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в Nature в грудні 1990
@uk
name
Interleukin-1 receptor antagonist reduces mortality from endotoxin shock
@en
Interleukin-1 receptor antagonist reduces mortality from endotoxin shock
@nl
type
label
Interleukin-1 receptor antagonist reduces mortality from endotoxin shock
@en
Interleukin-1 receptor antagonist reduces mortality from endotoxin shock
@nl
prefLabel
Interleukin-1 receptor antagonist reduces mortality from endotoxin shock
@en
Interleukin-1 receptor antagonist reduces mortality from endotoxin shock
@nl
P2093
P356
P1433
P1476
Interleukin-1 receptor antagonist reduces mortality from endotoxin shock
@en
P2093
Bergenfeldt M
Thompson RC
P2888
P304
P356
10.1038/348550A0
P407
P577
1990-12-01T00:00:00Z
P6179
1046337914