about
Lifeguard/neuronal membrane protein 35 regulates Fas ligand-mediated apoptosis in neurons via microdomain recruitmentThe death receptor antagonist FAIM promotes neurite outgrowth by a mechanism that depends on ERK and NF-kapp B signalingThe death receptor antagonist FLIP-L interacts with Trk and is necessary for neurite outgrowth induced by neurotrophinsThe novel gamma secretase inhibitor RO4929097 reduces the tumor initiating potential of melanomaMu-opioid receptor activation prevents apoptosis following serum withdrawal in differentiated SH-SY5Y cells and cortical neurons via phosphatidylinositol 3-kinase.Krüppel-like factor 4 (KLF4) regulates the miR-183~96~182 cluster under physiologic and pathologic conditions.MiR-182 overexpression in tumourigenesis of high-grade serous ovarian carcinoma.BRD4 sustains melanoma proliferation and represents a new target for epigenetic therapyTNFα sensitizes neuroblastoma cells to FasL-, cisplatin- and etoposide-induced cell death by NF-κB-mediated expression of Fas.Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant MelanomaMYCN repression of Lifeguard/FAIM2 enhances neuroblastoma aggressivenessIdentification of metastasis-suppressive microRNAs in primary melanomamiR-30b/30d regulation of GalNAc transferases enhances invasion and immunosuppression during metastasis.MicroRNA-497 impairs the growth of chemoresistant neuroblastoma cells by targeting cell cycle, survival and vascular permeability genes.Hedgehog pathway blockade inhibits melanoma cell growth in vitro and in vivo.MicroRNA-182 targets SMAD7 to potentiate TGFβ-induced epithelial-mesenchymal transition and metastasis of cancer cells.microRNAs as pharmacological targets in cancer.Combined miRNA profiling and proteomics demonstrates that different miRNAs target a common set of proteins to promote colorectal cancer metastasis.Patient-derived xenografts for childhood solid tumors: a valuable tool to test new drugs and personalize treatments.BRG1/SMARCA4 is essential for neuroblastoma cell viability through modulation of cell death and survival pathways.Fas apoptosis inhibitory molecules: more than death-receptor antagonists in the nervous system.Optimization of rhabdomyosarcoma disseminated disease assessment by flow cytometry.Modulation of chemotherapeutic drug resistance in neuroblastoma SK-N-AS cells by the neural apoptosis inhibitory protein and miR-520f.MicroRNA-22 is induced by vitamin D and contributes to its antiproliferative, antimigratory and gene regulatory effects in colon cancer cells.The long form of Fas apoptotic inhibitory molecule is expressed specifically in neurons and protects them against death receptor-triggered apoptosis.SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150.FAIM-L is an IAP-binding protein that inhibits XIAP ubiquitinylation and protects from Fas-induced apoptosis.Hedgehog Pathway Inhibition Hampers Sphere and Holoclone Formation in Rhabdomyosarcoma.miR-99a reveals two novel oncogenic proteins E2F2 and EMR2 and represses stemness in lung cancer.BCL-XL regulates TNF-alpha-mediated cell death independently of NF-kappaB, FLIP and IAPs.Reelin induces the detachment of postnatal subventricular zone cells and the expression of the Egr-1 through Erk1/2 activation.Ligand-dependent Hedgehog pathway activation in Rhabdomyosarcoma: the oncogenic role of the ligands.MicroRNA-200, associated with metastatic breast cancer, promotes traits of mammary luminal progenitor cells.Mechanisms of inactivation of the tumour suppressor gene RHOA in colorectal cancer.Reactive oxygen species and p38 mitogen-activated protein kinase activate Bax to induce mitochondrial cytochrome c release and apoptosis in response to malonate.Targeting of epigenetic regulators in neuroblastoma.Nuevas estrategias terapéuticas para el neuroblastoma basadas en el uso de microRNAsInterplay Between ncRNAs and Cellular Communication: A Proposal for Understanding Cell-Specific Signaling PathwaysFunctional high-throughput screening reveals miR-323a-5p and miR-342-5p as new tumor-suppressive microRNA for neuroblastomaSIVA-1 regulates apoptosis and synaptic function by modulating XIAP interaction with the death receptor antagonist FAIM-L
P50
Q24319929-82867EBA-0BC5-4637-8053-1E2F79D85950Q28571207-8CE04D61-5334-4768-B171-DD8CF95BD08EQ28580900-D22AFEA1-C70F-4A21-813E-AF23B869AE11Q28744417-9A10DBE2-B03E-4DC0-9E58-F15094F787BDQ33186448-36A2133A-D826-4C31-A609-CE9A9A7576E7Q33688638-9118500E-4213-4C35-B2FF-39985BB98A22Q34253391-35178BAC-9729-4025-86F8-4A881D721813Q34626550-58AF2B43-3C2B-4E8B-95FB-3A6F35FCB663Q35609210-294AF790-EEFE-403A-8BDB-6B67AF335876Q35815596-BA6A120F-1195-4767-A106-FE9E9A3B912BQ35966204-1E5C4995-4016-4281-BC69-E4B9395CE389Q36047432-1376C30D-66EB-49F8-A3E7-2FF3A3C30AECQ36926211-134BF74E-E12F-4E8F-80BD-E40755E25F78Q36962575-90BB9D48-FEBE-46DB-B8E5-012FB304923DQ37370438-DDA77DBF-8D24-4295-A869-7C878B7FE64AQ37533326-7B72726C-CBBB-49DF-A180-1B7B7C1BB32DQ38093917-482526F3-9545-4C21-89A6-95BA2C90C980Q38722886-8B08889B-195A-48CD-AE08-BEA12DA82AA3Q38741974-4B9B165A-3828-4AE6-B91E-1A9E907932CEQ38784675-ADAD1DDA-4CB4-4FCB-9CBB-725AE812F578Q38888419-10AC76AE-24FF-4BE3-9566-534E4BBD2CD0Q38963016-F4641BA5-7873-4088-8FED-DD0541B0B45BQ38964665-77B24B8A-59F7-4E70-A6F4-778A4AECFABEQ39397632-070D5BDE-645F-41F7-8910-671589949084Q40066489-0B32D7AE-C480-4A58-8571-363C19E443C3Q40444666-B132D28C-0102-4E34-89EB-A68657A9EF1FQ42251118-C3599149-73D3-4ACE-9DCC-4ED280B84661Q42323550-515B0623-1995-4A58-AE15-83DA2962B30CQ45992649-6A84D7B8-685B-4913-B69D-B89C10642AEBQ46508943-C33FC578-4371-4F58-BD23-A05982E16371Q46973343-0B1D4718-09B3-4ED3-9E39-E350611649B7Q47841646-018FCC2D-751E-48E7-BA05-E898B08E7028Q50020865-C177243B-4EED-4521-BE3E-245731895EB0Q50067187-5F63B7E2-7808-4495-8807-063B48CDC701Q50704525-9A7C9998-2355-4397-9BC8-54241DB7D756Q52560224-B6BE4BF6-95F3-4B39-9D64-2D8DE632AF1EQ61760921-B4852E15-690D-45FC-87FE-AB68FDDEAD11Q64084436-991CF924-2FA9-416E-952E-BC12FB752F36Q64241705-9A5770F8-DBE6-45DB-92DC-86269FB9241FQ89518410-0B960424-EF4E-46A6-9E0C-4C9AD728A1AE
P50
description
researcher ORCID ID = 0000-0003-0916-3618
@en
wetenschapper
@nl
name
Miguel F Segura
@ast
Miguel F Segura
@en
Miguel F Segura
@es
Miguel F Segura
@nl
type
label
Miguel F Segura
@ast
Miguel F Segura
@en
Miguel F Segura
@es
Miguel F Segura
@nl
prefLabel
Miguel F Segura
@ast
Miguel F Segura
@en
Miguel F Segura
@es
Miguel F Segura
@nl
P106
P21
P31
P496
0000-0003-0916-3618