Selective blockade of spinal D2DR by levo-corydalmine attenuates morphine tolerance via suppressing PI3K/Akt-MAPK signaling in a MOR-dependent manner

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Selective blockade of spinal D2DR by levo-corydalmine attenuates morphine tolerance via suppressing PI3K/Akt-MAPK signaling in a MOR-dependent manner

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scientific article published on 14 November 2018

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wetenschappelijk artikel

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наукова стаття, опублікована в листопаді 2018

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name

Selective blockade of spinal D ...... ling in a MOR-dependent manner

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Selective blockade of spinal D ...... ling in a MOR-dependent manner

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label

Selective blockade of spinal D ...... ling in a MOR-dependent manner

@en

Selective blockade of spinal D ...... ling in a MOR-dependent manner

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Selective blockade of spinal D ...... ling in a MOR-dependent manner

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Selective blockade of spinal D ...... ling in a MOR-dependent manner

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P1476

Selective blockade of spinal D ...... ling in a MOR-dependent manner

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P2093

Bing Yan

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Bo-Yang Yu

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Nan Jiang

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Wen-Ling Dai

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Xin-Tong Liu

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Yi-Ni Bao

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P2860

The expanding roles of Gβγ subunits in G protein-coupled receptor signaling and drug action

The physiology, signaling, and pharmacology of dopamine receptors

Enhanced morphine analgesia in mice lacking beta-arrestin 2

Role of D1/D2 dopamine and N-methyl-D-aspartate (NMDA) receptors in morphine tolerance and dependence in mice

Effects of the dopamine D2 allosteric modulator, PAOPA, on the expression of GRK2, arrestin-3, ERK1/2, and on receptor internalization

Antinociceptive potentiation and attenuation of tolerance by intrathecal β-arrestin 2 small interfering RNA in rats

Opioid receptor-triggered spinal mTORC1 activation contributes to morphine tolerance and hyperalgesia

Potentiation of opioid analgesia in dopamine2 receptor knock-out mice: evidence for a tonically active anti-opioid system

Drug addictions. Molecular and cellular endpoints.

The role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics.

P2888

s12276-018-0175-1

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1-12

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scholarly article

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10.1038/S12276-018-0175-1

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P407

English

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P478

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P50

Ji-Hua Liu

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2018-11-14T00:00:00Z

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P698

30429454

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P921

molecular medicine

molecular biology

P932

6235923

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