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The Potential of Vitamin D-Regulated Intracellular Signaling Pathways as Targets for Myeloid Leukemia TherapyMicroRNAs181 regulate the expression of p27Kip1 in human myeloid leukemia cells induced to differentiate by 1,25-dihydroxyvitamin D3Vitamin D and differentiation in cancer.Vitamin D3-driven signals for myeloid cell differentiation--implications for differentiation therapyMicroRNA-32 upregulation by 1,25-dihydroxyvitamin D3 in human myeloid leukemia cells leads to Bim targeting and inhibition of AraC-induced apoptosis.Inhibition of Cot1/Tlp2 oncogene in AML cells reduces ERK5 activation and up-regulates p27Kip1 concomitant with enhancement of differentiation and cell cycle arrest induced by silibinin and 1,25-dihydroxyvitamin D(3).NADPH-cytochrome P450 reductase is regulated by all-trans retinoic acid and by 1,25-dihydroxyvitamin D3 in human acute myeloid leukemia cells.ERK 5/MAPK pathway has a major role in 1α,25-(OH)2 vitamin D3-induced terminal differentiation of myeloid leukemia cells.Differentiation therapy of acute myeloid leukemia.Non-receptor protein tyrosine kinases signaling pathways in normal and cancer cells.DNA Repair in Despair-Vitamin D Is Not Fair.Different susceptibilities to 1,25-dihydroxyvitamin D3-induced differentiation of AML cells carrying various mutations.Activation of intracellular signaling pathways is necessary for an increase in VDR expression and its nuclear translocationGenes encoding transcription factors have self-control: how important is this for cell differentiation?Regulation of FOXP3 expression in myeloid cells in response to all-trans-retinoic acid, interleukin 2 and transforming growth factor β
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P50
description
researcher ORCID ID = 0000-0002-1941-0275
@en
wetenschapper
@nl
name
Elzbieta Gocek
@ast
Elzbieta Gocek
@en
Elzbieta Gocek
@es
Elzbieta Gocek
@nl
type
label
Elzbieta Gocek
@ast
Elzbieta Gocek
@en
Elzbieta Gocek
@es
Elzbieta Gocek
@nl
prefLabel
Elzbieta Gocek
@ast
Elzbieta Gocek
@en
Elzbieta Gocek
@es
Elzbieta Gocek
@nl
P31
P496
0000-0002-1941-0275