about
Total synthesis of the fumiquinazoline alkaloids: solid-phase studies.Inhibitors of neutrophil recruitment identified using transgenic zebrafish to screen a natural product library.New patented histone deacetylase inhibitors.Editor's Highlight: Transgenic Zebrafish Reporter Lines as Alternative In Vivo Organ Toxicity Models.Aquaporins: Novel Targets for Age-Related Ocular Disorders.Synthesis and evaluation of tryprostatin B and demethoxyfumitremorgin C analogues.SB939, a novel potent and orally active histone deacetylase inhibitor with high tumor exposure and efficacy in mouse models of colorectal cancer.Total solid phase syntheses of the quinazoline alkaloids: verrucines A and B and anacine.Preclinical metabolism and disposition of SB939 (Pracinostat), an orally active histone deacetylase inhibitor, and prediction of human pharmacokinetics.Humanizing the zebrafish liver shifts drug metabolic profiles and improves pharmacokinetics of CYP3A4 substrates.Design, Synthesis, and Preclinical Evaluation of Fused Pyrimidine-Based Hydroxamates for the Treatment of Hepatocellular Carcinoma.Structure and ligand-based design of mTOR and PI3-kinase inhibitors leading to the clinical candidates VS-5584 (SB2343) and SB2602.Structure-based design of PDK1 inhibitors.Total synthesis of the fumiquinazoline alkaloids: solution-phase studiesTotal Synthesis of the Quinazoline Alkaloids (-)-Fumiquinazoline G and (-)-Fiscalin BAntibody neutralization of microbiota-derived circulating peptidoglycan dampens inflammation and ameliorates autoimmunity
P50
Q30856051-AF6E0B7E-6AD6-417A-B060-03D4E7EEF7F6Q35057067-366BE9FE-2060-44A6-8AE0-7965F459C2DAQ37638742-77B871B1-F82A-4BCB-A6C7-508D6A50AD5EQ39030456-276A9695-9B86-40A6-AD02-B30BB43F5613Q39385934-199DC349-079D-4DC5-97E6-FCC99E0630B6Q40884008-FDD02F8A-ABCC-419B-ABCB-C5292E464BD1Q43144734-B1DAEACD-4726-4BFF-851B-CB7B62F005B9Q43831941-3204A432-599F-4F9B-BC4D-920B9FE6B3FDQ45356046-A4A03B3D-A11A-4BCA-9B66-9DEA640A5AFBQ46507025-E6F26FA4-99A4-405A-820E-C82EC9E7CB72Q48185225-E9395049-C719-4860-A402-BB934C684CCCQ53255090-15CA186C-E91B-47A1-9E5E-7D387C3C16BEQ54547290-C17A454B-41E7-4C27-A644-61A37ACFFBEDQ73798878-7EFCB4FF-C270-4CCD-AA1F-AD53E1446DE9Q74837735-F097A592-45B9-431B-9238-6506C18BAEE2Q92129002-E910BFC1-C2B2-45B8-B6F1-F7A3EAB03D13
P50
description
researcher ORCID ID = 0000-0002-7959-7377
@en
wetenschapper
@nl
name
Haishan Wang
@ast
Haishan Wang
@en
Haishan Wang
@es
Haishan Wang
@nl
type
label
Haishan Wang
@ast
Haishan Wang
@en
Haishan Wang
@es
Haishan Wang
@nl
prefLabel
Haishan Wang
@ast
Haishan Wang
@en
Haishan Wang
@es
Haishan Wang
@nl
P31
P496
0000-0002-7959-7377