The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities
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Homeostatic modulation of cell surface KDR and Flt1 expression and expression of the vascular endothelial cell growth factor (VEGF) receptor mRNAs by VEGFDrusen complement components C3a and C5a promote choroidal neovascularizationVascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cellsHost microenvironment in breast cancer development: inflammatory and immune cells in tumour angiogenesis and arteriogenesisG-Protein-coupled receptors as potential drug candidates in preeclampsia: targeting the relaxin/insulin-like family peptide receptor 1 for treatment and preventionEndothelial fatty acid transport: role of vascular endothelial growth factor BVascular endothelial growth factor-B in physiology and diseaseThe crystal structure of human placenta growth factor-1 (PlGF-1), an angiogenic protein, at 2.0 A resolutionVascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cellsMapping the charged residues in the second immunoglobulin-like domain of the vascular endothelial growth factor/placenta growth factor receptor Flt-1 required for binding and structural stabilityDifferential downregulation of vascular endothelial growth factor by dexamethasone in normoxic and hypoxic rat glioma cellsVascular endothelial growth factor (VEGF)-driven actin-based motility is mediated by VEGFR2 and requires concerted activation of stress-activated protein kinase 2 (SAPK2/p38) and geldanamycin-sensitive phosphorylation of focal adhesion kinaseVascular endothelial growth factor KDR receptor signaling potentiates tumor necrosis factor-induced tissue factor expression in endothelial cells.Modulation of angiogenesis by a tetrameric tripeptide that antagonizes vascular endothelial growth factor receptor 1.Placenta growth factor: potential role in pregnancy.Targetting VEGF in anti-angiogenic and anti-tumour therapy: where are we now?The vasa vasorum in diseased and nondiseased arteriesGrowth factor signaling pathways in vascular development.Vascular endothelial growth factor receptor-1 and neuropilin-2 form complexes.VEGF receptor 1 signaling is essential for osteoclast development and bone marrow formation in colony-stimulating factor 1-deficient mice.The discovery of placenta growth factor and its biological activity.Placental growth factor induces FosB and c-Fos gene expression via Flt-1 receptors.Placenta growth factor expression is regulated by hydrogen peroxide in vascular smooth muscle cells.Substitution of C-terminus of VEGFR-2 with VEGFR-1 promotes VEGFR-1 activation and endothelial cell proliferation.Vascular endothelial growth factor receptor family genes: when did the three genes phylogenetically segregate?Vascularity, angiogenesis and angiogenic factors in leukemias and myelodysplastic syndromes.Prognostic significance of VEGFR1/Flt-1 immunoexpression in colorectal carcinoma.Angiogenic factors in the central nervous system.The Role of Vascular Endothelial Growth Factor Receptor-1 Signaling in the Recovery from Ischemia.Vascular endothelial growth factor enhances macrophage clearance of apoptotic cells.Functional-morphological parameters, aqueous flare and cytokines in macular oedema with branch retinal vein occlusion after ranibizumab.CD4+VEGFR1(HIGH) T cell as a novel Treg subset regulates inflammatory bowel disease in lymphopenic micePlacental Growth Factor Is Secreted by the Human Endometrium and Has Potential Important Functions during Embryo Development and Implantation.Placenta growth factor and vascular endothelial growth factor a have differential, cell-type specific patterns of expression in vascular cells.VEGF/VEGFR signalling as a target for inhibiting angiogenesis.Targeting VEGF and Its Receptors for the Treatment of Osteoarthritis and Associated Pain.Flt-1 in colorectal cancer cells is required for the tumor invasive effect of placental growth factor through a p38-MMP9 pathway.Neutrophil elastase cleaves VEGF to generate a VEGF fragment with altered activity.Exercise training and peripheral arterial disease.Insights into mechanisms behind arteriogenesis: what does the future hold?
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P2860
The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities
description
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
im Juli 1996 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published in Journal of Biological Chemistry
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в липні 1996
@uk
name
The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities
@en
The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities
@nl
type
label
The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities
@en
The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities
@nl
prefLabel
The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities
@en
The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities
@nl
P2093
P356
P1476
The vascular endothelial growt ...... cyte activation and chemotaxis
@en
P2093
P304
17629-17634
P356
10.1074/JBC.271.30.17629
P407
P577
1996-07-01T00:00:00Z