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Parameter trajectory analysis to identify treatment effects of pharmacological interventionsA computational model for the analysis of lipoprotein distributions in the mouse: translating FPLC profiles to lipoprotein metabolismConcept Development of the Eindhoven Diabetes Education Simulator Project.An In Vivo Magnetic Resonance Spectroscopy Study of the Effects of Caloric and Non-Caloric Sweeteners on Liver Lipid Metabolism in RatsMuscle-type specific autophosphorylation of CaMKII isoforms after paced contractions.Parameter adaptations during phenotype transitions in progressive diseases.Quantifying the composition of human skin for glucose sensor developmentPrediction of muscle energy states at low metabolic rates requires feedback control of mitochondrial respiratory chain activity by inorganic phosphate.Optimal experiment design for model selection in biochemical networks.Model-Based Quantification of the Systemic Interplay between Glucose and Fatty Acids in the Postprandial State.Systems biology from micro-organisms to human metabolic diseases: the role of detailed kinetic models.A Bayesian approach to targeted experiment design.A physiology-based model describing heterogeneity in glucose metabolism: the core of the Eindhoven Diabetes Education Simulator (E-DES)Effects of low-stearate palm oil and high-stearate lard high-fat diets on rat liver lipid metabolism and glucose tolerance.Dynamic modelling and analysis of biochemical networks: mechanism-based models and model-based experiments.Integration of the metabolic and cardiovascular effects of exercise.Magnitude and control of mitochondrial sensitivity to ADP.Poly(ADP-ribose) polymerase regulates myocardial calcium handling in doxorubicin-induced heart failureParameter uncertainty in biochemical models described by ordinary differential equations.A genome-scale metabolic network reconstruction of tomato (Solanum lycopersicum L.) and its application to photorespiratory metabolism.Mathematical modeling confirms the length-dependency of telomere shortening.A structured, minimal parameter model of the central nitrogen metabolism in Saccharomyces cerevisiae: the prediction of the behavior of mutants.Computational evidence for protein-mediated fatty acid transport across the sarcolemma.The glutamate synthase (GOGAT) of Saccharomyces cerevisiae plays an important role in central nitrogen metabolism.In vivo heat shock preconditioning mitigates calcium overload during ischaemia/reperfusion in the isolated, perfused rat heart.beta-Adrenergic activation reveals impaired cardiac calcium handling at early stage of diabetes.Mathematical modelling of the calcium-left ventricular pressure relationship in the intact diabetic rat heart.Computational modelling identifies the impact of subtle anatomical variations between amphibian and mammalian skeletal muscle on spatiotemporal calcium dynamics.A systems biology approach reveals the physiological origin of hepatic steatosis induced by liver X receptor activation.Parameter estimation in models combining signal transduction and metabolic pathways: the dependent input approach.Computational model of excitable cell indicates ATP free energy dynamics in response to calcium oscillations are undampened by cytosolic ATP buffers.Mathematical modeling of vascular endothelial layer maintenance: the role of endothelial cell division, progenitor cell homing, and telomere shortening.On the identifiability of pharmacokinetic parameters in dynamic contrast-enhanced imaging.In vivo and in silico dynamics of the development of Metabolic Syndrome.Leukocytes of exceptionally old persons display ultra-short telomeresComputational modelling of energy balance in individuals with Metabolic SyndromeMetabolic modeling of Saccharomyces cerevisiae using the optimal control of homeostasis: a cybernetic model definitionThe cell factory needs a model of a factoryAltered calcium handling is an early sign of streptozotocin-induced diabetic cardiomyopathyA computational model of postprandial adipose tissue lipid metabolism derived using human arteriovenous stable isotope tracer data
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description
researcher ORCID ID = 0000-0001-9375-4730
@en
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Natal A van Riel
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Natal A van Riel
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Natal A van Riel
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Natal A van Riel
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Natal A van Riel
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Natal A van Riel
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Natal A van Riel
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Natal A van Riel
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Natal A van Riel
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Natal A van Riel
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Natal A van Riel
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Natal A van Riel
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P1153
6602100075
P31
P496
0000-0001-9375-4730