about
Platform process for production of monoclonal antibodies for research purposes - improvement optionSequencing the CHO DXB11 genome reveals regional variations in genomic stability and haploidy.Network reconstruction of the mouse secretory pathway applied on CHO cell transcriptome data.Functional reconstitution of insulin receptor binding site from non-binding receptor fragments.Dimeric fragment of the insulin receptor alpha-subunit binds insulin with full holoreceptor affinity.Expression and characterization of a 70-kDa fragment of the insulin receptor that binds insulin. Minimizing ligand binding domain of the insulin receptor.N-glycosylation increases the circulatory half-life of human growth hormone.Posttranslational N-glycosylation takes place during the normal processing of human coagulation factor VII.Structural basis of the aberrant receptor binding properties of hagfish and lamprey insulins.A new secreted insect protein belonging to the immunoglobulin superfamily binds insulin and related peptides and inhibits their activities.Role of insulin receptor dimerization domains in ligand binding, cooperativity, and modulation by anti-receptor antibodies.Engineered CHO cells for production of diverse, homogeneous glycoproteins.Deep sequencing reveals different compositions of mRNA transcribed from the F8 gene in a panel of FVIII-producing CHO cell lines.Glycoengineering design options for IgG1 in CHO cells using precise gene editing.Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormonesToward genome-scale models of the Chinese hamster ovary cells: incentives, status and perspectivesLigand-induced conformational change in the minimized insulin receptorSpecificity of insulin and insulin-like growth factor I receptors investigated using chimeric mini-receptors. Role of C-terminal of receptor alpha subunitAlanine scanning mutagenesis of insulinCorrelations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use
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description
researcher ORCID ID = 0000-0002-2594-7722
@en
wetenschapper
@nl
name
Claus Kristensen
@ast
Claus Kristensen
@en
Claus Kristensen
@es
Claus Kristensen
@nl
type
label
Claus Kristensen
@ast
Claus Kristensen
@en
Claus Kristensen
@es
Claus Kristensen
@nl
prefLabel
Claus Kristensen
@ast
Claus Kristensen
@en
Claus Kristensen
@es
Claus Kristensen
@nl
P21
P31
P496
0000-0002-2594-7722