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Prevention of heart failure in mice by an antiviral agent that inhibits type 5 cardiac adenylyl cyclaseCommon mechanisms for calorie restriction and adenylyl cyclase type 5 knockout models of longevityAdenylyl cyclase type 5 in cardiac disease, metabolism, and aging.Calorie restriction can reverse, as well as prevent, aging cardiomyopathy.Type 5 adenylyl cyclase increases oxidative stress by transcriptional regulation of manganese superoxide dismutase via the SIRT1/FoxO3a pathway.β2-adrenergic receptors inhibit the expression of collagen type II in growth plate chondrocytes by stimulating the AP-1 factor Jun-B.Beta2-adrenergic receptors expressed on murine chondrocytes stimulate cellular growth and inhibit the expression of Indian hedgehog and collagen type X.
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description
researcher ORCID ID = 0000-0002-6771-1646
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wetenschapper
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Lo Lai
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Lo Lai
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Lo Lai
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Lo Lai
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Lo Lai
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Lo Lai
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Lo Lai
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Lo Lai
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Lo Lai
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0000-0002-6771-1646