about
4,5-diarylisoxazole Hsp90 chaperone inhibitors: potential therapeutic agents for the treatment of cancerCombining hit identification strategies: fragment-based and in silico approaches to orally active 2-aminothieno[2,3-d]pyrimidine inhibitors of the Hsp90 molecular chaperoneStructure-based design of agents targeting the bacterial ribosome.Hsp90 inhibitors and drugs from fragment and virtual screening.The medicinal chemist's toolbox: an analysis of reactions used in the pursuit of drug candidates.Off-rate screening (ORS) by surface plasmon resonance. An efficient method to kinetically sample hit to lead chemical space from unpurified reaction products.Application of Off-Rate Screening in the Identification of Novel Pan-Isoform Inhibitors of Pyruvate Dehydrogenase Kinase.Dynamic undocking and the quasi-bound state as tools for drug discovery.Intramolecular nitrone dipolar cycloadditions: control of regioselectivity and synthesis of naturally-occurring spirocyclic alkaloidsFive Years of the KNIME Vernalis Cheminformatics Community ContributionEstablishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1
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description
onderzoeker
@nl
researcher ORCID ID = 0000-0003-0683-5693
@en
name
Stephen D Roughley
@ast
Stephen D Roughley
@en
Stephen D Roughley
@es
Stephen D Roughley
@nl
type
label
Stephen D Roughley
@ast
Stephen D Roughley
@en
Stephen D Roughley
@es
Stephen D Roughley
@nl
prefLabel
Stephen D Roughley
@ast
Stephen D Roughley
@en
Stephen D Roughley
@es
Stephen D Roughley
@nl
P106
P1153
6507875416
P31
P496
0000-0003-0683-5693