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Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell deathSerum miRNAs miR-206, 143-3p and 374b-5p as potential biomarkers for amyotrophic lateral sclerosis (ALS).A new zebrafish model produced by TILLING of SOD1-related amyotrophic lateral sclerosis replicates key features of the disease and represents a tool for in vivo therapeutic screening.Inhibition of the mitochondrial calcium uniporter rescues dopaminergic neurons in pink1-/- zebrafish.Zebrafish-based small molecule screens for novel cardiovascular drugs.Loss of function of parathyroid hormone receptor 1 induces Notch-dependent aortic defects during zebrafish vascular development.
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description
researcher ORCID ID = 0000-0002-3804-0150
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wetenschapper
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name
Marc Da Costa
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Marc Da Costa
@en
Marc Da Costa
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Marc Da Costa
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type
label
Marc Da Costa
@ast
Marc Da Costa
@en
Marc Da Costa
@es
Marc Da Costa
@nl
prefLabel
Marc Da Costa
@ast
Marc Da Costa
@en
Marc Da Costa
@es
Marc Da Costa
@nl
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56002420200
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0000-0002-3804-0150