about
Removal of LIF (leukemia inhibitory factor) results in increased vitamin A (retinol) metabolism to 4-oxoretinol in embryonic stem cellsmiRNA and mammalian male germ cellsA novel germ cell protein, SPIF (sperm PKA interacting factor), is essential for the formation of a PKA/TCP11 complex that undergoes conformational and phosphorylation changes upon capacitationMouse spermatocytes express CYP2E1 and respond to acrylamide exposureIdentification and characterization of a novel Mt-retrotransposon highly represented in the female mouse germline.A unique combination of male germ cell miRNAs coordinates gonocyte differentiation.Dynamin regulates specific membrane fusion events necessary for acrosomal exocytosis in mouse spermatozoa.Antioxidant systems and oxidative stress in the testesThe rise of testicular germ cell tumours: the search for causes, risk factors and novel therapeutic targets.Antioxidant systems and oxidative stress in the testes.The genetic consequences of paternal acrylamide exposure and potential for amelioration.Epididymal CYP2E1 plays a critical role in acrylamide-induced DNA damage in spermatozoa and paternally mediated embryonic resorptions†.Adenylyl cyclase isoforms in rat testis and spermatozoa from the cauda epididymidis.Glycogen synthase kinase 3 regulates acrosomal exocytosis in mouse spermatozoa via dynamin phosphorylation.Progesterone receptor regulation by retinoic acid in the human breast cancer cell line T-47D.Chronic acrylamide exposure in male mice induces DNA damage to spermatozoa; Potential for amelioration by resveratrol.Jumping the gun: smoking constituent BaP causes premature primordial follicle activation and impairs oocyte fusibility through oxidative stress.Understanding the Villain: DMBA-induced preantral ovotoxicity involves selective follicular destruction and primordial follicle activation through PI3K/Akt and mTOR signaling.Analysis of the mechanism by which calcium negatively regulates the tyrosine phosphorylation cascade associated with sperm capacitation.Vitamin A regulation of BMP4 expression in the male germ line.Identification and characterization of a novel splice variant of mouse and rat cytochrome b5/cytochrome b5 reductase.Chronic Acrylamide Exposure in Male Mice Results in Elevated DNA Damage in the Germline and Heritable Induction of CYP2E1 in the Testes.CXCR4/SDF1 interaction inhibits the primordial to primary follicle transition in the neonatal mouse ovary.Staying alive: PI3K pathway promotes primordial follicle activation and survival in response to 3MC-induced ovotoxicity.Improved methods of DNA extraction from human spermatozoa that mitigate experimentally-induced oxidative DNA damage.Chronic exposure to acrylamide induces DNA damage in male germ cells of miceExpression of c-Kit receptor mRNA and protein in the developing, adult and irradiated rodent testisEstradiol induction of retinoic acid receptors in human breast cancer cellsPaternal impacts on development: identification of genomic regions vulnerable to oxidative DNA damage in human spermatozoaOxidative Stress Dysregulates Protein Homeostasis Within the Male Germ LineTransgenerational inheritance: how impacts to the epigenetic and genetic information of parents affect offspring healthAdvances in human primordial follicle activation and premature ovarian insufficiency
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P50
description
researcher ORCID ID = 0000-0002-7758-7757
@en
wetenschapper
@nl
name
Shaun D Roman
@ast
Shaun D Roman
@en
Shaun D Roman
@nl
type
label
Shaun D Roman
@ast
Shaun D Roman
@en
Shaun D Roman
@nl
prefLabel
Shaun D Roman
@ast
Shaun D Roman
@en
Shaun D Roman
@nl
P106
P31
P496
0000-0002-7758-7757