about
Ambra1 regulates autophagy and development of the nervous systemReduced cathepsins B and D cause impaired autophagic degradation that can be almost completely restored by overexpression of these two proteases in Sap C-deficient fibroblastsThe dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy.Zebrafish ambra1a and ambra1b knockdown impairs skeletal muscle development.AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation.The role of autophagy during development in higher eukaryotes.Ambra1 at a glance.Autophagy induction impairs migration and invasion by reversing EMT in glioblastoma cells.Differential apoptotic effect and metabolism of N-acetylsphingosine and N-hexanoylsphingosine in CHP-100 human neurotumor cells.Cysteine residues are critical for chemokine receptor CXCR2 functional properties.N-Oleoylethanolamine inhibits glucosylation of natural ceramides in CHP-100 neuroepithelioma cells: possible implications for apoptosis.P-Glycoprotein is not a key target for the chemosensitizing effect of 1-phenyl-2-decanoylamino-3-morpholino-1-propanol in HepG2 cells exposed to doxorubicin.Differential chemosensitizing effect of two glucosylceramide synthase inhibitors in hepatoma cells.Chemokine receptor CXCR2 regulates the functional properties of AMPA-type glutamate receptor GluR1 in HEK cells.Ordering ceramide-induced cell detachment and apoptosis in human neuroepithelioma.Signalling pathways involved in the chemotactic activity of CXCL12 in cultured rat cerebellar neurons and CHP100 neuroepithelioma cells.Unleashing the Ambra1-Beclin 1 complex from dynein chains: Ulk1 sets Ambra1 free to induce autophagy.Caspase inhibition shifts neuroepithelioma cell response to okadaic acid from apoptosis to an apoptotic-like form of death.Ligand-independent CXCR2 dimerization.Expression of AMPA-type glutamate receptors in HEK cells and cerebellar granule neurons impairs CXCL2-mediated chemotaxis.Erratum: Corrigendum: AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradationCeramide-Induced Apoptosis Is Mediated by Caspase Activation Independently from Retinoblastoma Protein Post-Translational ModificationApoptosis induced by doxorubicin in neurotumor cells is divorced from drug effects on ceramide accumulation and may involve cell cycle-dependent caspase activation
P50
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P50
description
onderzoeker
@nl
researcher ORCID ID = 0000-0002-5748-1541
@en
name
Sabrina Di Bartolomeo
@ast
Sabrina Di Bartolomeo
@en
Sabrina Di Bartolomeo
@es
Sabrina Di Bartolomeo
@nl
type
label
Sabrina Di Bartolomeo
@ast
Sabrina Di Bartolomeo
@en
Sabrina Di Bartolomeo
@es
Sabrina Di Bartolomeo
@nl
prefLabel
Sabrina Di Bartolomeo
@ast
Sabrina Di Bartolomeo
@en
Sabrina Di Bartolomeo
@es
Sabrina Di Bartolomeo
@nl
P106
P1153
7004397499
P21
P31
P496
0000-0002-5748-1541