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Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival.Control of voltage-gated potassium channel Kv2.2 expression by pyruvate-isocitrate cycling regulates glucose-stimulated insulin secretion.Pdx-1 activates islet α- and β-cell proliferation via a mechanism regulated by transient receptor potential cation channels 3 and 6 and extracellular signal-regulated kinases 1 and 2.A Pdx-1-Regulated Soluble Factor Activates Rat and Human Islet Cell Proliferation.A critical role for CRM1 in regulating HOXA gene transcription in CALM-AF10 leukemias.Physiological mechanisms of sustained fumagillin-induced weight loss.The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase.β Cell tone is defined by proglucagon peptides through cAMP signalingCreation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing
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description
researcher ORCID ID = 0000-0002-8270-7039
@en
wetenschapper
@nl
name
Jonathan M Haldeman
@ast
Jonathan M Haldeman
@en
Jonathan M Haldeman
@es
Jonathan M Haldeman
@nl
type
label
Jonathan M Haldeman
@ast
Jonathan M Haldeman
@en
Jonathan M Haldeman
@es
Jonathan M Haldeman
@nl
prefLabel
Jonathan M Haldeman
@ast
Jonathan M Haldeman
@en
Jonathan M Haldeman
@es
Jonathan M Haldeman
@nl
P106
P21
P31
P496
0000-0002-8270-7039