about
Characterization of the imprinted polycomb gene L3MBTL, a candidate 20q tumour suppressor gene, in patients with myeloid malignanciesJAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatinImprinting of the human L3MBTL gene, a polycomb family member located in a region of chromosome 20 deleted in human myeloid malignanciesSomatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2International network of cancer genome projects.Transcriptional regulation of the stem cell leukemia gene (SCL)--comparative analysis of five vertebrate SCL lociJanus kinase deregulation in leukemia and lymphomaSelf-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansionHydroxyurea compared with anagrelide in high-risk essential thrombocythemiaSCL and related hemopoietic helix-loop-helix transcription factorsBone marrow pathology in essential thrombocythemia: interobserver reliability and utility for identifying disease subtypesGuideline for investigation and management of adults and children presenting with a thrombocytosisA kinase-independent function of CDK6 links the cell cycle to tumor angiogenesisInactivating CUX1 mutations promote tumorigenesisRFP represses transcriptional activation by bHLH transcription factorsGata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic developmentL3mbtl, the mouse orthologue of the imprinted L3MBTL, displays a complex pattern of alternative splicing and escapes genomic imprintingA novel mode of enhancer evolution: the Tal1 stem cell enhancer recruited a MIR element to specifically boost its activityThe European Hematology Association Roadmap for European Hematology Research: a consensus documentDefinition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: a prospective study.Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid LeukemiaDirecting oncogenic fusion genes into stem cells via an SCL enhancer.Pathogenesis and management of essential thrombocythemia.Distinct clinical phenotypes associated with JAK2V617F reflect differential STAT1 signalingIdentification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cells.JAK2V617F promotes replication fork stalling with disease-restricted impairment of the intra-S checkpoint responseLIF-independent JAK signalling to chromatin in embryonic stem cells uncovered from an adult stem cell disease.Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell PopulationsTranscriptional link between blood and bone: the stem cell leukemia gene and its +19 stem cell enhancer are active in bone cellsThe Ph-positive and Ph-negative myeloproliferative neoplasms: some topical pre-clinical and clinical issues.MPL mutations in myeloproliferative disorders: analysis of the PT-1 cohort.Double jeopardy from a single translocation: deletions of the derivative chromosome 9 in chronic myeloid leukemia.Independently acquired biallelic JAK2 mutations are present in a minority of patients with essential thrombocythemia.The JAK2 46/1 haplotype predisposes to MPL-mutated myeloproliferative neoplasmsGenome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators.Origins and functional consequences of somatic mitochondrial DNA mutations in human cancerGenetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms.The SCL transcriptional network and BMP signaling pathway interact to regulate RUNX1 activity.Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells.Effect of mutation order on myeloproliferative neoplasms.
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P50
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onderzoeker
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researcher ORCID ID = 0000-0002-9795-0218
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name
Anthony R Green
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Anthony R Green
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Anthony R Green
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Anthony R Green
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Anthony R Green
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Anthony R Green
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Anthony R Green
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Anthony Green
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Green AR
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Anthony R Green
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Anthony R Green
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Anthony R Green
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Anthony R Green
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0000-0002-9795-0218
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lccn-n2007072959