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Biomphalaria glabrata transcriptome: cDNA microarray profiling identifies resistant- and susceptible-specific gene expression in haemocytes from snail strains exposed to Schistosoma mansoniIdentification of Schistosoma mansoni gender-associated gene transcripts by cDNA microarray profilingCharacterization of the Schistosoma transcriptome opens up the world of helminth genomicsDrug-induced exposure of Schistosoma mansoni antigens SmCD59a and SmKK7Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of SchistosomiasisAnti-schistosomal intervention targets identified by lifecycle transcriptomic analysesThe diterpenoid 7-keto-sempervirol, derived from Lycium chinense, displays anthelmintic activity against both Schistosoma mansoni and Fasciola hepaticaDevelopmentally regulated expression, alternative splicing and distinct sub-groupings in members of the Schistosoma mansoni venom allergen-like (SmVAL) gene family.Use of genomic DNA as an indirect reference for identifying gender-associated transcripts in morphologically identical, but chromosomally distinct, Schistosoma mansoni cercariae.Patterns of chemokine expression in models of Schistosoma mansoni inflammation and infection reveal relationships between type 1 and type 2 responses and chemokines in vivo.The Biomphalaria glabrata DNA methylation machinery displays spatial tissue expression, is differentially active in distinct snail populations and is modulated by interactions with Schistosoma mansoniWhole genome analysis of a schistosomiasis-transmitting freshwater snail.Excreted/secreted Schistosoma mansoni venom allergen-like 9 (SmVAL9) modulates host extracellular matrix remodelling gene expression.Cytosine methylation is a conserved epigenetic feature found throughout the phylum Platyhelminthes.Human IgG1 Responses to Surface Localised Schistosoma mansoni Ly6 Family Members Drop following Praziquantel Treatment.Cytosine methylation regulates oviposition in the pathogenic blood fluke Schistosoma mansoni.DISMISS: detection of stranded methylation in MeDIP-Seq data.Platyhelminth Venom Allergen-Like (VAL) proteins: revealing structural diversity, class-specific features and biological associations across the phylum.Schistosoma mansoni hemozoin modulates alternative activation of macrophages via specific suppression of Retnla expression and secretion.Glycomics-driven discoveries in schistosome research.Schistosoma mansoni arginase shares functional similarities with human orthologs but depends upon disulphide bridges for enzymatic activity.Gender-associated gene expression in two related strains of Schistosoma japonicum.Rethinking Schistosomiasis Vaccine Development: Synthetic Vesicles.(Epi)genetic Inheritance in Schistosoma mansoni: A Systems Approach.Medicine. Halting harmful helminths.Neoclerodane Diterpenoids from Reehal Fatima, Teucrium yemense.IL-10 is critical for host resistance and survival during gastrointestinal helminth infection.Protein and small non-coding RNA-enriched extracellular vesicles are released by the pathogenic blood fluke Schistosoma mansoniMolecular characterization of a 20.8-kDa Schistosoma mansoni antigen. Sequence similarity to tegumental associated antigens and dynein light chains.Disease fingerprinting with cDNA microarrays reveals distinct gene expression profiles in lethal type 1 and type 2 cytokine-mediated inflammatory reactions.Human IgE response to the Schistosoma haematobium 22.6 kDa antigen.Molecular characterization of omega-1: a hepatotoxic ribonuclease from Schistosoma mansoni eggs.Schistosome egg production is dependent upon the activities of two developmentally regulated tyrosinases.Dioecious Schistosoma mansoni express divergent gene repertoires regulated by pairing.The anti-fecundity effect of 5-azacytidine (5-AzaC) on Schistosoma mansoni is linked to dis-regulated transcription, translation and stem cell activities.Histone methylation changes are required for life cycle progression in the human parasite Schistosoma mansoni.Methyl-CpG-binding (SmMBD2/3) and chromobox (SmCBX) proteins are required for neoblast proliferation and oviposition in the parasitic blood fluke Schistosoma mansoni.An Abies procera-derived tetracyclic triterpene containing a steroid-like nucleus core and a lactone side chain attenuates in vitro survival of both Fasciola hepatica and Schistosoma mansoniCombining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoniProgrammed genome editing of the omega-1 ribonuclease of the blood fluke,
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description
researcher ORCID ID = 0000-0002-3932-5502
@en
wetenschapper
@nl
name
Karl F Hoffmann
@ast
Karl F Hoffmann
@en
Karl F Hoffmann
@nl
type
label
Karl F Hoffmann
@ast
Karl F Hoffmann
@en
Karl F Hoffmann
@nl
prefLabel
Karl F Hoffmann
@ast
Karl F Hoffmann
@en
Karl F Hoffmann
@nl
P106
P31
P496
0000-0002-3932-5502