about
Conserved phosphoryl transfer mechanisms within kinase families and the role of the C8 proton of ATP in the activation of phosphoryl transferIn vitro anti-plasmodial activity of Dicoma anomala subsp. gerrardii (Asteraceae): identification of its main active constituent, structure-activity relationship studies and gene expression profilingDesign, synthesis, and In vitro antituberculosis activity of 2(5H)-Furanone derivatives.Cytotoxic activity of expanded coordination bis-thiosemicarbazones and copper complexes thereof.Investigation of the cytotoxic implications of metal chelators against melanoma and approaches to improve the cytotoxicity profiles of metal coordinating agents.Increased generation of intracellular reactive oxygen species initiates selective cytotoxicity against the MCF-7 cell line resultant from redox active combination therapy using copper-thiosemicarbazone complexes.Improved cytotoxicity of pyridyl-substituted thiosemicarbazones against MCF-7 when used as metal ionophores.Selective induction of oxidative stress in cancer cells via synergistic combinations of agents targeting redox homeostasis.Structure-activity relationship study of sesquiterpene lactones and their semi-synthetic amino derivatives as potential antitrypanosomal products.Differential inhibition of adenylylated and deadenylylated forms of M. tuberculosis glutamine synthetase as a drug discovery platform.Metathesis reactions for the synthesis of ring-fused carbazoles.The Evaluation of Metal Co-ordinating Bis-Thiosemicarbazones as Potential Anti-malarial AgentsDevelopment of pyridyl thiosemicarbazones as highly potent agents for the treatment of malaria after oral administrationIn Vitro Efficacies, ADME, and Pharmacokinetic Properties of Phenoxazine Derivatives Active against Mycobacterium tuberculosis
P50
Q34187629-910FFD4E-29BF-497C-9E55-ABA83F1B9073Q35431970-875EB700-04B3-4863-A241-5453CB52BACDQ36062032-4664574D-5C8E-44F1-9690-188BD50F75B5Q38744982-972F70E2-7638-4B83-8EC7-25F74F156150Q38759275-6BB23B2E-6321-4129-8760-C286ED5A96EDQ38788219-76BEE84E-1BAB-4712-A79D-0E0F3F751816Q38810643-493B8846-73F1-4E8F-BF49-E48EAA6BF384Q38869883-AEE825E9-D701-499D-A847-DFABD077746CQ39012409-7576436E-7E5E-454B-A736-2A73459E2D68Q42369452-61116DAA-D24B-4B5A-88BB-E6F36CC0F17FQ46832384-37D5235D-302C-404E-A9D5-30693EC1B9F5Q56379971-17BFB73F-A39A-4A1B-B72E-224BE770A667Q92039262-16938A5E-B1DC-4B83-BE2F-67DE03DCD137Q92707846-C79EFE1D-36F0-4394-9CD4-D8B4341A4CCC
P50
description
Forscher
@de
chercheur
@fr
investigador
@es
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
研究者
@zh
name
Christopher J Parkinson
@ast
Christopher J Parkinson
@en
Christopher J Parkinson
@es
Christopher J Parkinson
@nl
type
label
Christopher J Parkinson
@ast
Christopher J Parkinson
@en
Christopher J Parkinson
@es
Christopher J Parkinson
@nl
altLabel
Christopher J Parkinson, C J Parkinson
@en
prefLabel
Christopher J Parkinson
@ast
Christopher J Parkinson
@en
Christopher J Parkinson
@es
Christopher J Parkinson
@nl
P106
P1153
55069640600
7102253041
P21
P31
P496
0000-0003-4547-7091