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Physicochemical characterization of the endotoxins from Coxiella burnetii strain Priscilla in relation to their bioactivitiesSolution scattering suggests cross-linking function of telethonin in the complex with titinThe influence of protein concentration on oligomer structure and catalytic function of two pyruvate decarboxylases.Cross-talk in the A1-ATPase from Methanosarcina mazei Go1 due to nucleotide binding.Triticum durum metallothionein. Isolation of the gene and structural characterization of the protein using solution scattering and molecular modeling.Dimer formation of subunit G of the yeast V-ATPase.Supercooled smectic nanoparticles: influence of the matrix composition and in vitro cytotoxicity.Influence of stabilizer systems on the properties and phase behavior of supercooled smectic nanoparticles.Consistent picture of the reversible thermal unfolding of hen egg-white lysozyme from experiment and molecular dynamicsAdvances in structure analysis using small-angle scattering in solution.Acronycine derivatives as promising antitumor agents.Physicochemical properties of bacterial glycopolymers in relation to bioactivity.Design of novel antitumor DNA alkylating agents: the benzacronycine series.X-ray scattering of non-crystalline biological systems using synchrotron radiation.Supramolecular structure of enterobacterial wild-type lipopolysaccharides (LPS), fractions thereof, and their neutralization by Pep19-2.5.Covalent binding of antitumor benzoacronycines to double-stranded DNA induces helix opening and the formation of single-stranded DNA: unique consequences of a novel DNA-bonding mechanism.A novel series of cytotoxic iridoid glucosides derived from aucubin: design, synthesis and structure-activity relationships.Synthesis, cytotoxic activity, and DNA binding properties of antitumor cis-1,2-dihydroxy-1,2-dihydrobenzo[b]acronycine cinnamoyl esters.Physicochemical characterization and biological activity of lipooligosaccharides and lipid A from Neisseria meningitidis.Synthesis and cytotoxicity of a novel iridoid glucoside derived from aucubin.Biophysical characterization of triacyl monosaccharide lipid a partial structures in relation to bioactivity.Synthesis and cytotoxic activity of benzo[a]pyrano[3,2-h] and [2,3-i]xanthone analogues of psorospermine, acronycine, and benzo[a]acronycine.Temperature dependence of the binding of endotoxins to the polycationic peptides polymyxin B and its nonapeptide.Design, synthesis, and cytotoxic activity of Michael acceptors and enol esters in the benzo[b]acronycine series.New antitubulin derivatives in the combretastatin A4 series: synthesis and biological evaluation.Synthesis and cytotoxic activity of benzo[c][1,7] and [1,8]phenanthrolines analogues of nitidine and fagaronine.Synthesis and cytotoxic activity of pyranocarbazole analogues of ellipticine and acronycine.Biophysical characterization of endotoxin inactivation by NK-2, an antimicrobial peptide derived from mammalian NK-lysin.Enhancement of endotoxin neutralization by coupling of a C12-alkyl chain to a lactoferricin-derived peptide.Effects of urea and trimethylamine-N-oxide (TMAO) on the interactions of lysozyme in solution.Ligand-dependent structural changes in the V(1) ATPase from Manduca sexta.Counteraction of urea by trimethylamine N-oxide is due to direct interactionThermodynamic analysis of the lipopolysaccharide-dependent resistance of gram-negative bacteria against polymyxin B.The lipopolysaccharide of Brucella abortus BvrS/BvrR mutants contains lipid A modifications and has higher affinity for bactericidal cationic peptides.Ultrafast X-ray solution scattering reveals different reaction pathways in the photolysis of triruthenium dodecacarbonyl (Ru3(CO)12) after ultraviolet and visible excitation.Investigation into the interaction of recombinant human serum albumin with Re-lipopolysaccharide and lipid A.Preparation and structural investigations of colloidal dispersions prepared from cubic monoglyceride-water phases.Biophysical characterization of the interaction of high-density lipoprotein (HDL) with endotoxins.Synthesis of 6-dialkylaminoalkylamino pyrano[2,3-c]acridones and benzo[b]pyrano[3,2-h]acridones: soluble acronycine analogues with increased cytotoxic activity.Studies on structure-function relationships of indolepyruvate decarboxylase from Enterobacter cloacae, a key enzyme of the indole acetic acid pathway.
P50
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P50
name
Michel H J Koch
@ast
Michel H J Koch
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Michel H J Koch
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Michel H J Koch
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type
label
Michel H J Koch
@ast
Michel H J Koch
@en
Michel H J Koch
@es
Michel H J Koch
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prefLabel
Michel H J Koch
@ast
Michel H J Koch
@en
Michel H J Koch
@es
Michel H J Koch
@nl
P244
P21
P214
140147663131060552465
P244
nb2014009227
P31
P735
P7859
lccn-nb2014009227