about
A mouse model uncovers LKB1 as an UVB-induced DNA damage sensor mediating CDKN1A (p21WAF1/CIP1) degradationUncoupling of the LKB1-AMPKalpha energy sensor pathway by growth factors and oncogenic BRAFProtein arginine methyltransferase 5 regulates ERK1/2 signal transduction amplitude and cell fate through CRAFKinase fusions are frequent in Spitz tumours and spitzoid melanomas.Acyl protein thioesterase 1 and 2 (APT-1, APT-2) inhibitors palmostatin B, ML348 and ML349 have different effects on NRAS mutant melanoma cellsPhosphoproteomic Analyses of NRAS(G12) and NRAS(Q61) Mutant Melanocytes Reveal Increased CK2α Kinase Levels in NRAS(Q61) Mutant Cells.Dual MEK/AKT inhibition with trametinib and GSK2141795 does not yield clinical benefit in metastatic NRAS-mutant and wild-type melanoma.The lincRNA MIRAT binds to IQGAP1 and modulates the MAPK pathway in NRAS mutant melanoma.ATP-Competitive Inhibitors Midostaurin and Avapritinib Have Distinct Resistance Profiles in Exon 17-Mutant KITWriters, readers and erasers of RNA modifications in cancer
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description
researcher ORCID ID = 0000-0003-0547-1752
@en
wetenschapper
@nl
name
Rosaura Esteve-Puig
@ast
Rosaura Esteve-Puig
@en
Rosaura Esteve-Puig
@es
Rosaura Esteve-Puig
@nl
type
label
Rosaura Esteve-Puig
@ast
Rosaura Esteve-Puig
@en
Rosaura Esteve-Puig
@es
Rosaura Esteve-Puig
@nl
prefLabel
Rosaura Esteve-Puig
@ast
Rosaura Esteve-Puig
@en
Rosaura Esteve-Puig
@es
Rosaura Esteve-Puig
@nl
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26421623600
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0000-0003-0547-1752