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Signaling mechanisms and disrupted cytoskeleton in the diphenyl ditelluride neurotoxicityVimentin phosphorylation as a target of cell signaling mechanisms induced by 1alpha,25-dihydroxyvitamin D3 in immature rat testesMembrane-initiated actions of thyroid hormones on the male reproductive system.Dual action of chronic ethanol treatment on LPS-induced response in C6 glioma cells.Cytoskeleton as a Target of Quinolinic Acid Neurotoxicity: Insight from Animal Models.Acute ethanol exposure disrupts actin cytoskeleton and generates reactive oxygen species in c6 cells.Homocysteine induces hypophosphorylation of intermediate filaments and reorganization of actin cytoskeleton in C6 glioma cells.Effect of the branched-chain alpha-keto acids accumulating in maple syrup urine disease on S100B release from glial cells.Thyroid hormones reorganize the cytoskeleton of glial cells through Gfap phosphorylation and Rhoa-dependent mechanisms.Branched-chain amino acids accumulating in maple syrup urine disease induce morphological alterations in C6 glioma cells probably through reactive species.Branched-chain alpha-keto acids accumulating in maple syrup urine disease induce reorganization of phosphorylated GFAP in C6-glioma cells.Hyperthyroidism in the developing rat testis is associated with oxidative stress and hyperphosphorylated vimentin accumulation.Roundup disrupts male reproductive functions by triggering calcium-mediated cell death in rat testis and Sertoli cells.Disrupted cytoskeletal homeostasis, astrogliosis and apoptotic cell death in the cerebellum of preweaning rats injected with diphenyl ditelluride.In vivo treatment with diphenyl ditelluride induces neurodegeneration in striatum of young rats: implications of MAPK and Akt pathways.Cross-talk among intracellular signaling pathways mediates the diphenyl ditelluride actions on the hippocampal cytoskeleton of young rats.Diphenyl ditelluride induces hypophosphorylation of intermediate filaments through modulation of DARPP-32-dependent pathways in cerebral cortex of young rats.Homocysteine induces cytoskeletal remodeling and production of reactive oxygen species in cultured cortical astrocytes.Acute intrastriatal administration of quinolinic acid provokes hyperphosphorylation of cytoskeletal intermediate filament proteins in astrocytes and neurons of rats.Hyperhomocysteinemia selectively alters expression and stoichiometry of intermediate filament and induces glutamate- and calcium-mediated mechanisms in rat brain during development.Alterations of PI3K and Akt signaling pathways in the hippocampus and hypothalamus of Wistar rats treated with highly palatable food.Cytoskeleton of human mononuclear cells as a possible peripheral marker for phenylalanine neurotoxicity in PKU.Effect of propionic and methylmalonic acids on the in vitro phosphorylation of intermediate filaments from cerebral cortex of rats during development.Alpha-keto-beta-methylvaleric acid increases the in vitro phosphorylation of intermediate filaments in cerebral cortex of young rats through the gabaergic system.Evidence that the branched-chain alpha-keto acids accumulating in maple syrup urine disease induce morphological alterations and death in cultured astrocytes from rat cerebral cortex.Congenital hypothyroidism is associated with intermediate filament misregulation, glutamate transporters down-regulation and MAPK activation in developing rat brain.Propionic and methylmalonic acids increase cAMP levels in slices of cerebral cortex of young rats via adrenergic and glutamatergic mechanisms.Involvement of calcium-dependent mechanisms in T3-induced phosphorylation of vimentin of immature rat testis.Homocysteine activates calcium-mediated cell signaling mechanisms targeting the cytoskeleton in rat hippocampus.Evidence that intracellular Ca2+ mediates the effect of alpha-ketoisocaproic acid on the phosphorylating system of cytoskeletal proteins from cerebral cortex of immature rats.Morphological alterations and cell death provoked by the branched-chain alpha-amino acids accumulating in maple syrup urine disease in astrocytes from rat cerebral cortex.Propylthiouracil-induced congenital hypothyroidism upregulates vimentin phosphorylation and depletes antioxidant defenses in immature rat testis.Alpha-ketoisocaproic acid increases phosphorylation of intermediate filament proteins from rat cerebral cortex by mechanisms involving Ca2+ and cAMP.Effects of in vivo treatment with diphenyl ditelluride on the phosphorylation of cytoskeletal proteins in cerebral cortex and hippocampus of rats.Methylphenidate disrupts cytoskeletal homeostasis and reduces membrane-associated lipid content in juvenile rat hippocampus.Vitamin D3 Reverses the Hippocampal Cytoskeleton Imbalance But Not Memory Deficits Caused by Ovariectomy in Adult Wistar Rats.Developmental neurotoxicity of the hippocampus following in utero exposure to methylmercury: impairment in cell signaling.Kynurenic Acid Prevents Cytoskeletal Disorganization Induced by Quinolinic Acid in Mixed Cultures of Rat Striatum.Methylglyoxal-induced cytotoxicity in neonatal rat brain: a role for oxidative stress and MAP kinases.Cytoskeleton of cortical astrocytes as a target to proline through oxidative stress mechanisms.
P50
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P50
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Regina Pessoa-Pureur
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Regina Pessoa-Pureur
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Regina Pessoa-Pureur
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Regina Pessoa-Pureur
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Regina Pessoa-Pureur
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Regina Pessoa-Pureur
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Regina Pessoa-Pureur
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Regina Pessoa-Pureur
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Regina Pessoa-Pureur
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Regina Pessoa-Pureur
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Regina Pessoa-Pureur
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