about
Bioresponsive polymer-based nucleic acid carriers.siRNA-Loaded Polyion Complex Micelle Decorated with Charge-Conversional Polymer Tuned to Undergo Stepwise Response to Intra-Tumoral and Intra-Endosomal pHs for Exerting Enhanced RNAi Efficacy.Regulated protonation of polyaspartamide derivatives bearing repeated aminoethylene side chains for efficient intracellular siRNA delivery with minimal cytotoxicity.Fine-tuning of charge-conversion polymer structure for efficient endosomal escape of siRNA-loaded calcium phosphate hybrid micelles.Systemic siRNA delivery to a spontaneous pancreatic tumor model in transgenic mice by PEGylated calcium phosphate hybrid micelles.Polyion complex stability and gene silencing efficiency with a siRNA-grafted polymer delivery system.Targeted systemic delivery of siRNA to cervical cancer model using cyclic RGD-installed unimer polyion complex-assembled gold nanoparticles.Engineering Tumour Cell-Binding Synthetic Polymers with Sensing Dense Transporters Associated with Aberrant Glutamine Metabolism.Acidic pH-responsive siRNA conjugate for reversible carrier stability and accelerated endosomal escape with reduced IFNα-associated immune response.Multilayered polyion complexes with dissolvable silica layer covered by controlling densities of cRGD-conjugated PEG chains for cancer-targeted siRNA delivery.Utility of the 2-Nitrobenzenesulfonamide Group as a Chemical Linker for Enhanced Extracellular Stability and Cytosolic Cleavage in siRNA-Conjugated Polymer Systems.Artificial Control of Gene Silencing Activity Based on siRNA Conjugation with Polymeric Molecule Having Coil-Globule Transition Behavior.Functional polymer-based siRNA delivery carrier that recognizes site-specific biosignals.Precisely regulated nanoarchitecture comprised of gold nanotemplate and unimer polyion complex for systemic delivery of siRNA.Influence of RNA Strand Rigidity on Polyion Complex Formation with Block Catiomers.An Ethylenediamine-based Switch to Render the Polyzwitterion Cationic at Tumorous pH for Effective Tumor Accumulation of Coated Nanomaterials.Effect of multiple cyclic RGD peptides on tumor accumulation and intratumoral distribution of IRDye 700DX-conjugated polymers.In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancersPoly(ethylene glycol)-poly(lysine) block copolymer-ubenimex conjugate targets aminopeptidase N and exerts an antitumor effect in hepatocellular carcinoma stem cellsAccelerated polymer-polymer click conjugation by freeze-thaw treatmentSmart multilayered assembly for biocompatible siRNA delivery featuring dissolvable silica, endosome-disrupting polycation, and detachable PEGPrecise engineering of siRNA delivery vehicles to tumors using polyion complexes and gold nanoparticlesPoly(vinyl alcohol) boosting therapeutic potential of p-boronophenylalanine in neutron capture therapy by modulating metabolismPoly( N-isopropylacrylamide)-Based Polymer-Inducing Isothermal Hydrophilic-to-Hydrophobic Phase Transition via Detachment of Hydrophilic Acid-Labile MoietyPyruvate Responsiveness Based on α-Oxohydrazone Formation for Intracellular siRNA Release from Polyion Complex-Based Carriers
P50
Q38269564-0FE931C9-426C-4515-8FF5-8770F4004EBBQ38815969-FB442D90-EA35-495F-94AF-D3CCF966A3FDQ38918266-B530E413-B41D-4050-ADDF-EBAAD1A86994Q39006047-F4B9BFD9-ACF2-4A79-8790-E57012A42438Q39033142-22BC5212-00D7-4E81-BAA6-A206A059B112Q39669960-14ACE9D7-B3BC-4F75-821D-73FDFE9AB2D0Q40596550-46F68C02-F46B-4A25-86BE-D57CC404935AQ41075531-A07D42FA-4A68-4ABD-B8B0-1754BBBA4D2BQ46543595-C7A601AA-2F8B-4F9B-A17C-8FE28731FDFBQ48144871-1F2641C9-08FB-45DA-A19D-43089F14B0FCQ48214605-75F0520E-0A41-4653-8491-DD62C7105A09Q49127206-9C9DC742-05B8-4173-B650-AD0450A40BDEQ50035856-F08C6EED-DF27-4E37-BF6A-211E373FDFD9Q51423714-2E6B0178-DD6E-40C9-867E-86A9100F9BF7Q51562391-5EF58AE4-C787-473E-9C26-704D846C3328Q52670335-2DD6C228-D614-4497-81D5-8A82B9E553E4Q55130405-0724E601-44BA-445D-9EAB-9B02AAA18C04Q64094904-669003DC-5188-4B4E-9FE7-D13A26286EA4Q64122994-303C9098-E1E5-4EE7-9394-243D06706216Q84496144-4A99B5E2-9530-433F-80AB-14E4554FFC84Q84628222-EC210AB7-C5C6-4552-81C0-69E6B915D82BQ87607521-5CFB4C87-0F1A-4A45-A56A-E97A752AE52FQ89498431-7B437687-BBB8-4B63-977F-7651588DF8CDQ90638307-4073908B-785B-4871-B4E0-B0D1AD4F8667Q92038182-69D42C15-5FD1-4ACF-B2AB-3A16A8B1D078
P50
description
researcher ORCID ID = 0000-0002-0264-8746
@en
wetenschapper
@nl
name
Hiroyasu Takemoto
@ast
Hiroyasu Takemoto
@en
Hiroyasu Takemoto
@es
Hiroyasu Takemoto
@nl
type
label
Hiroyasu Takemoto
@ast
Hiroyasu Takemoto
@en
Hiroyasu Takemoto
@es
Hiroyasu Takemoto
@nl
prefLabel
Hiroyasu Takemoto
@ast
Hiroyasu Takemoto
@en
Hiroyasu Takemoto
@es
Hiroyasu Takemoto
@nl
P31
P496
0000-0002-0264-8746