about
Bronchial epithelial cells are rendered insensitive to glucocorticoid transactivation by transforming growth factor-β1.Transforming growth factor-β impairs glucocorticoid activity in the A549 lung adenocarcinoma cell line.Glucocorticoid Insensitivity in Virally Infected Airway Epithelial Cells Is Dependent on Transforming Growth Factor-β Activity.Glucocorticoid resistance of migration and gene expression in a daughter MDA-MB-231 breast tumour cell line selected for high metastatic potential.Glucocorticoid-resistant asthma and novel anti-inflammatory drugs.Mechanisms of glucocorticoid action and insensitivity in airways disease.Heterogeneity in mechanisms influencing glucocorticoid sensitivity: the need for a systems biology approach to treatment of glucocorticoid-resistant inflammation.Biased signalling from the glucocorticoid receptor: Renewed opportunity for tailoring glucocorticoid activity.Pro-inflammatory mediators increase levels of the noncoding RNA GAS5 in airway smooth muscle and epithelial cells.Cortisol limits selected actions of synthetic glucocorticoids in the airway epithelium.The Coagulant Factor Xa Induces Protease-Activated Receptor-1 and Annexin A2-Dependent Airway Smooth Muscle Cytokine Production and Cell Proliferation.EZH2 function in immune cell developmentCasein Kinase 1δ/ε Inhibitor, PF670462 Attenuates the Fibrogenic Effects of Transforming Growth Factor-β in Pulmonary FibrosisPolycomb repressive complex 2 is a critical mediator of allergic inflammationGenome organization in immune cells: unique challengesEpigenomic drivers of immune dysfunction in aging
P50
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P50
description
researcher ORCID ID = 0000-0002-6057-1855
@en
wetenschapper
@nl
name
Christine R Keenan
@ast
Christine R Keenan
@en
Christine R Keenan
@es
Christine R Keenan
@nl
type
label
Christine R Keenan
@ast
Christine R Keenan
@en
Christine R Keenan
@es
Christine R Keenan
@nl
prefLabel
Christine R Keenan
@ast
Christine R Keenan
@en
Christine R Keenan
@es
Christine R Keenan
@nl
P1153
37118918300
P21
P31
P496
0000-0002-6057-1855