about
HTLV-1-infected CD4+ T-cells display alternative exon usages that culminate in adult T-cell leukemiaTET-catalyzed oxidation of intragenic 5-methylcytosine regulates CTCF-dependent alternative splicingOncogene- and drug resistance-associated alternative exon usage in acute myeloid leukemia (AML).Chromatin redistribution of the DEK oncoprotein represses hTERT transcription in leukemiasHow mRNA is misspliced in acute myelogenous leukemia (AML)?HTLV-1 bZIP factor HBZ promotes cell proliferation and genetic instability by activating OncomiRs.Alternative splicing signatures discriminate ATL cells from untransformed CD4+ counterparts deriving from HTLV-1 infected individuals.Tax alters telomerase activity through both quantitative and qualitative hTERT transcriptional dysregulations.Tax promotes the expression of the alternative spliced isoform CD44v10 by slowing down the elongating RNA polymerase II.HTLV-1 modulates alternative splicing in CD4+ T cells in vivo.Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemiaSHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival
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description
researcher ORCID ID = 0000-0003-1893-3338
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wetenschapper
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name
Morgan Thenoz
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Morgan Thenoz
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Morgan Thenoz
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Morgan Thenoz
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type
label
Morgan Thenoz
@ast
Morgan Thenoz
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Morgan Thenoz
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Morgan Thenoz
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prefLabel
Morgan Thenoz
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Morgan Thenoz
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Morgan Thenoz
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Morgan Thenoz
@nl
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P496
0000-0003-1893-3338