about
At a supra-physiological concentration, human sexual hormones act as quorum-sensing inhibitorsA rapid in vivo colorimetric library screen for inhibitors of microbial respiration.Iminosugars as a new class of cholinesterase inhibitors.A direct label-free MALDI-TOF mass spectrometry based assay for the characterization of inhibitors of protein lysine methyltransferases.Holaphyllamine, a steroid, is able to induce defense responses in Arabidopsis thaliana and increases resistance against bacterial infection.New MKLP-2 inhibitors in the paprotrain series: Design, synthesis and biological evaluations.Relocation of Aurora B and survivin from centromeres to the central spindle impaired by a kinesin-specific MKLP-2 inhibitor.Hypervalent iodine-mediated oxidative cyclisation of p-hydroxy acetanilides to 1,2-dispirodienones.Combined treatment with galanthaminium bromide, a new cholinesterase inhibitor, and RS 67333, a partial agonist of 5-HT4 receptors, enhances place and object recognition in young adult and old rats.Benefit of 13-desmethyl spirolide C treatment in triple transgenic mouse model of Alzheimer disease: beta-amyloid and neuronal markers improvement.(-)-9-Dehydrogalanthaminium bromide, a new cholinesterase inhibitor, enhances place and object recognition memory in young and old rats.Rhodium(III)-Catalyzed Synthesis of Spiropiperidine Derivatives via C-H Activation.Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-2.Shogaol-huprine hybrids: dual antioxidant and anticholinesterase agents with β-amyloid and tau anti-aggregating properties.Further investigation of Paprotrain: Towards the conception of selective and multi-targeted CNS kinase inhibitors.Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes.Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes⁻4Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-3Potent acetylcholinesterase inhibitors: design, synthesis, and structure-activity relationships of bis-interacting ligands in the galanthamine seriesFormal total syntheses of aspidosperma alkaloids via a novel and general synthetic pathway based on an intramolecular Heck cyclizationA new access to dihydrotropones through ring expansion of spirocyclohexadienones: synthesis and mechanismKinetic study of the rearrangement of deuterium-labeled 4'-O-methylnorbelladine in Leucojum aestivum shoot cultures by mass spectrometry. Influence of precursor feeding on amaryllidaceae alkaloid accumulationNew potent human acetylcholinesterase inhibitors in the tetracyclic triterpene series with inhibitory potency on amyloid β aggregationCatalytic enantioselective vinylogous Mukaiyama-Michael addition of 2-silyloxyfurans to cyclic unsaturated oxo estersMild rhodium(iii)-catalyzed intramolecular annulation of benzamides with allylic alcohols to access azepinone derivativesBreakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-6An Efficient Total Synthesis of (+/-)-Galanthamine We are grateful to the CNRS for financial support, and the French Ministry of Education and Research for Ph.D grants to J.L.B. and E.G. Professor P. Potier is gratefully acknowledged for his interes
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description
Frans scheikundige
@nl
chimiste à l'Institut de Chimie des Substances Naturelles
@fr
researcher ORCID ID = 0000-0003-0693-0703
@en
name
Catherine Guillou
@ast
Catherine Guillou
@en
Catherine Guillou
@es
Catherine Guillou
@fr
Catherine Guillou
@nl
Catherine Guillou
@sl
type
label
Catherine Guillou
@ast
Catherine Guillou
@en
Catherine Guillou
@es
Catherine Guillou
@fr
Catherine Guillou
@nl
Catherine Guillou
@sl
prefLabel
Catherine Guillou
@ast
Catherine Guillou
@en
Catherine Guillou
@es
Catherine Guillou
@fr
Catherine Guillou
@nl
Catherine Guillou
@sl
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P21
P27
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P496
0000-0003-0693-0703