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Doxorubicin-loaded silk films: drug-silk interactions and in vivo performance in human orthotopic breast cancer.Surgery combined with controlled-release doxorubicin silk films as a treatment strategy in an orthotopic neuroblastoma mouse model.Impact of processing parameters on the haemocompatibility of Bombyx mori silk films.In vitro model of metastasis to bone marrow mediates prostate cancer castration resistant growth through paracrine and extracellular matrix factors.Tissue engineering a surrogate niche for metastatic cancer cellsFocal therapy of neuroblastoma using silk films to deliver kinase and chemotherapeutic agents in vivo.Polymeric biomaterials for stem cell bioengineering.PEGylated Silk Nanoparticles for Anticancer Drug Delivery.Establishment of subcellular fractionation techniques to monitor the intracellular fate of polymer therapeutics I. Differential centrifugation fractionation B16F10 cells and use to study the intracellular fate of HPMA copolymer - doxorubicin.A material-based platform to modulate fibronectin activity and focal adhesion assembly.Engineered extracellular matrices modulate the expression profile and feeder properties of bone marrow-derived human multipotent mesenchymal stromal cells.Functional immobilization of signaling proteins enables control of stem cell fate.Metabolic Reprogramming of Macrophages Exposed to Silk, Poly(lactic-co-glycolic acid), and Silica Nanoparticles.Silk nanoparticles: proof of lysosomotropic anticancer drug delivery at single-cell resolution.Matrix elasticity regulates the secretory profile of human bone marrow-derived multipotent mesenchymal stromal cells (MSCs).Comparison of the endocytic properties of linear and branched PEIs, and cationic PAMAM dendrimers in B16f10 melanoma cells.Manufacture and Drug Delivery Applications of Silk Nanoparticles.Endogenous bone morphogenetic proteins in human bone marrow-derived multipotent mesenchymal stromal cells.Soft and flexible poly(ethylene glycol) nanotubes for local drug delivery.The Biomedical Use of Silk: Past, Present, FutureIn vitro studies on space-conforming self-assembling silk hydrogels as a mesenchymal stem cell-support matrix suitable for minimally invasive brain applicationReverse-engineered silk hydrogels for cell and drug deliveryBiocompatibility assessment of silk nanoparticles: hemocompatibility and internalization by human blood cellsA Review of the Emerging Role of Silk for the Treatment of the EyeImpact of the hypoxic phenotype on the uptake and efflux of nanoparticles by human breast cancer cellsTightly anchored tissue-mimetic matrices as instructive stem cell microenvironmentsNanomedicines for the Delivery of BiologicsThe growth and differentiation of mesenchymal stem and progenitor cells cultured on aligned collagen matricesProlonged transendothelial migration of human haematopoietic stem and progenitor cells (HSPCs) towards hydrogel-released SDF1Unraveling the Impact of High-Order Silk Structures on Molecular Drug Binding and Release BehaviorsPEGylation-Dependent Metabolic Rewiring of Macrophages with Silk Fibroin Nanoparticles
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Friedrich Philipp Seib
@en
Philipp Seib
@ast
Philipp Seib
@es
Philipp Seib
@nl
type
label
Friedrich Philipp Seib
@en
Philipp Seib
@ast
Philipp Seib
@es
Philipp Seib
@nl
altLabel
Philipp Seib
@en
prefLabel
Friedrich Philipp Seib
@en
Philipp Seib
@ast
Philipp Seib
@es
Philipp Seib
@nl
P106
P1153
15840375700
P21
P31
P496
0000-0002-1955-1975