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Anaerobic enzyme.substrate structures provide insight into the reaction mechanism of the copper-dependent quercetin 2,3-dioxygenase.New insight into cofactor-free oxygenation from combined experimental and computational approachesX-ray structure of bovine pancreatic phospholipase A2 at atomic resolutionFunctional analysis of the copper-dependent quercetin 2,3-dioxygenase. 1. Ligand-induced coordination changes probed by X-ray crystallography: inhibition, ordering effect, and mechanistic insightsStructural basis for cofactor-independent dioxygenation of N-heteroaromatic compounds at the / -hydrolase foldOrigin of the Proton-transfer Step in the Cofactor-free (1H)-3-Hydroxy-4-oxoquinaldine 2,4-Dioxygenase: EFFECT OF THE BASICITY OF AN ACTIVE SITE HIS RESIDUEThe crystal structure of the human titin:obscurin complex reveals a conserved yet specific muscle M-band zipper moduleREFMAC5 dictionary: organization of prior chemical knowledge and guidelines for its useREFMAC5 for the refinement of macromolecular crystal structuresTargeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2α-mediated stress signalingThe light chains of kinesin-1 are autoinhibited.The Dynamic Localization of Cytoplasmic Dynein in Neurons Is Driven by Kinesin-1.Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection.Cofactor-independent oxidases and oxygenases.Keep it together: restraints in crystallographic refinement of macromolecule-ligand complexes.Single-crystal EPR study at 95 GHz of the type 2 copper site of the inhibitor-bound quercetin 2,3-dioxygenase.The Cannabinoid Receptor Interacting Proteins 1 of zebrafish are not required for morphological development, viability or fertility.Direct evidence for a peroxide intermediate and a reactive enzyme-substrate-dioxygen configuration in a cofactor-free oxidase.Crystallization and preliminary X-ray analysis of 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase from Arthrobacter nitroguajacolicus Rü61a: a cofactor-devoid dioxygenase of the alpha/beta-hydrolase-fold superfamily.SKIP controls lysosome positioning using a composite kinesin-1 heavy and light chain-binding domain.Model building, refinement and validation.Functional analysis of the copper-dependent quercetin 2,3-dioxygenase. 2. X-ray absorption studies of native enzyme and anaerobic complexes with the substrates quercetin and myricetin.EPR characterization of the mononuclear Cu-containing Aspergillus japonicus quercetin 2,3-dioxygenase reveals dramatic changes upon anaerobic binding of substrates.Online Raman spectroscopy for structural biology on beamline ID29 of the ESRF.A small-molecule activator of kinesin-1 drives remodeling of the microtubule network.Catalytic mechanism of cofactor-free dioxygenases and how they circumvent spin-forbidden oxygenation of their substrates.Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Roberto A Steiner
@ast
Roberto A Steiner
@en
Roberto A Steiner
@es
Roberto A Steiner
@nl
type
label
Roberto A Steiner
@ast
Roberto A Steiner
@en
Roberto A Steiner
@es
Roberto A Steiner
@nl
prefLabel
Roberto A Steiner
@ast
Roberto A Steiner
@en
Roberto A Steiner
@es
Roberto A Steiner
@nl
P108
P106
P21
P31
P496
0000-0001-7084-9745