about
Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumorsProtein kinase C phosphorylates ribosomal protein S6 kinase betaII and regulates its subcellular localization.A kinome-wide RNAi screen in Drosophila Glia reveals that the RIO kinases mediate cell proliferation and survival through TORC2-Akt signaling in glioblastomaOligomerization of G-protein-coupled receptors shown by selective co-immunoprecipitationMolecular cloning of CoA Synthase. The missing link in CoA biosynthesisMalignant astrocytic glioma: genetics, biology, and paths to treatmentUsing high-density DNA methylation arrays to profile copy number alterations.Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx.Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans.Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis.Therapeutic targeting of epidermal growth factor receptor in human cancer: successes and limitations.Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240.Integrated virus-host methylome analysis in head and neck squamous cell carcinoma.Functions and regulation of the 70kDa ribosomal S6 kinases.APOBEC3 genes: retroviral restriction factors to cancer drivers.The Genomics, Epigenomics, and Transcriptomics of HPV-Associated Oropharyngeal Cancer--Understanding the Basis of a Rapidly Evolving Disease.CD8+ T cell response to human papillomavirus 16 E7 is able to predict survival outcome in oropharyngeal cancer.CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma.S6K1 is acetylated at lysine 516 in response to growth factor stimulation.Histone acetyltransferases interact with and acetylate p70 ribosomal S6 kinases in vitro and in vivo.Regulation of ribosomal protein S6 kinases by ubiquitination.Receptor association and tyrosine phosphorylation of S6 kinases.p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells.APOBEC-mediated cytosine deamination links PIK3CA helical domain mutations to human papillomavirus-driven tumor development.When defense turns into attack: Antiviral cytidine deaminases linked to somatic mutagenesis in HPV-associated cancer.Pan-cancer deconvolution of tumour composition using DNA methylationAuthor Correction: Pan-cancer deconvolution of tumour composition using DNA methylationAuthor Correction: Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAnessFrequent HPV-independent p16/INK4A overexpression in head and neck cancerThe PTEN and INK4A/ARF tumor suppressors maintain myelolymphoid homeostasis and cooperate to constrain histiocytic sarcoma development in humansChemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAnessNOX4 Inhibition Potentiates Immunotherapy by Overcoming Cancer-Associated Fibroblast-Mediated CD8 T-cell Exclusion from TumorsInhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA RepairThe APOBEC3 genes and their role in cancer: insights from human papillomavirus
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P50
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wetenschapper
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հետազոտող
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Tim R Fenton
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Tim R Fenton
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Tim R Fenton
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Tim R Fenton
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Tim R Fenton
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Tim R Fenton
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Tim R Fenton
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Tim R Fenton
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Tim R Fenton
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Tim R Fenton
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Tim R Fenton
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Tim R Fenton
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P106
P1153
35480103200
P31
P496
0000-0002-4737-8233