about
Telomerase deficiency impairs glucose metabolism and insulin secretionDevelopmental Pathways Direct Pancreatic Cancer Initiation from Its Cellular OriginLifestyle impacts on the aging-associated expression of biomarkers of DNA damage and telomere dysfunction in human bloodSod2 haploinsufficiency does not accelerate aging of telomere dysfunctional miceRegeneration of the exocrine pancreas is delayed in telomere-dysfunctional mice.BRG1 promotes hepatocarcinogenesis by regulating proliferation and invasivenessOblique bile duct predisposes to the recurrence of bile duct stones.Dicer regulates differentiation and viability during mouse pancreatic cancer initiationLoss of ATM accelerates pancreatic cancer formation and epithelial-mesenchymal transition.The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinomaNr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation.Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma.The long-lived nature of clostridium perfringens iota toxin in mammalian cells induces delayed apoptosis.A cell-permeable fusion toxin as a tool to study the consequences of actin-ADP-ribosylation caused by the salmonella enterica virulence factor SpvB in intact cells.Telomerase gene mutations are associated with cirrhosis formation.Atypical flat lesions derive from pancreatic acinar cells.Salmonella enterica SpvB ADP-ribosylates actin at position arginine-177-characterization of the catalytic domain within the SpvB protein and a comparison to binary clostridial actin-ADP-ribosylating toxins.Hes1 Controls Exocrine Cell Plasticity and Restricts Development of Pancreatic Ductal Adenocarcinoma in a Mouse Model.
P50
Q24633376-2FD6AC84-1E44-4AF5-B2DA-DBC975D3A3EFQ26774942-68C6B31B-ACE7-4673-AAD4-67CDC7F6AA79Q30431195-6B151DC5-36B3-4179-97BD-4F16E6A274ECQ33694150-E6604596-F8CD-4475-95CA-BF36C364AF59Q33834033-69DAAA4A-6479-4697-8A15-02B43921B93AQ33898452-B55A5C2A-E0CF-4180-9647-91AD4FF5B30CQ34568369-CB40AA70-A4A1-46A7-953C-C7D46A46A571Q35161464-13CC6012-E939-4372-9E9B-5B344D78E4CEQ35941554-DB4E88AE-9286-4C56-A780-7D6A4C4049F4Q36384268-4F99E5A1-92EE-455C-9560-A4189A4F3A3DQ39156056-A5F3E906-6EB0-4E8E-89EF-DC4F8D858028Q41856856-9A0055E8-A380-47CD-A774-9A56E663707EQ42141687-E0201AC8-5DC9-4D92-BBFC-E968242B4076Q42831289-DDA6EDF3-F31D-44BE-B5AB-738FA2E1BFF5Q43444556-18549373-A1B3-42F2-881F-DC7D96EF31ACQ46862467-44FBB295-AE1F-4D03-8898-A118FA96E756Q46906519-D31DA8E2-FA1F-41DE-AA02-5443465E1006Q51496154-FE3EB789-B0A4-44B5-BAAA-4DB9CE11D048
P50
name
Guido von Figura
@ast
Guido von Figura
@en
Guido von Figura
@nl
type
label
Guido von Figura
@ast
Guido von Figura
@en
Guido von Figura
@nl
prefLabel
Guido von Figura
@ast
Guido von Figura
@en
Guido von Figura
@nl