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Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distributionGenetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966A genome-wide association study identifies protein quantitative trait loci (pQTLs)Genetic studies of body mass index yield new insights for obesity biologyTwelve type 2 diabetes susceptibility loci identified through large-scale association analysisGenome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controlsCommon variants near MC4R are associated with fat mass, weight and risk of obesitySix new loci associated with body mass index highlight a neuronal influence on body weight regulationA common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesityNew genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes riskDiscovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density ImputationA genome-wide association search for type 2 diabetes genes in African AmericansAnalysis of multiple data sets reveals no association between the insulin gene variable number tandem repeat element and polycystic ovary syndrome or related traits.Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors.Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetesEvaluation of common type 2 diabetes risk variants in a South Asian population of Sri Lankan descentVariants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight.Association between common variation at the FTO locus and changes in body mass index from infancy to late childhood: the complex nature of genetic association through growth and development.A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1qLife-course analysis of a fat mass and obesity-associated (FTO) gene variant and body mass index in the Northern Finland Birth Cohort 1966 using structural equation modeling.Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distributionNovel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studiesDefining the role of common variation in the genomic and biological architecture of adult human height.Common variants near ATM are associated with glycemic response to metformin in type 2 diabetesLarge-scale analysis of the relationship between CYP11A promoter variation, polycystic ovarian syndrome, and serum testosterone.Genome-wide associations for birth weight and correlations with adult diseaseNew genetic loci link adipose and insulin biology to body fat distribution.Type 2 diabetes TCF7L2 risk genotypes alter birth weight: a study of 24,053 individuals.Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes.New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolismMutations in HNF1A result in marked alterations of plasma glycan profileType 2 diabetes risk alleles are associated with reduced size at birthVariation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin.Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.Genes Associated with Pancreas Development and Function Maintain Open Chromatin in iPSCs Generated from Human Pancreatic Beta Cells.Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci.Detailed analysis of variation at and around mitochondrial position 16189 in a large Finnish cohort reveals no significant associations with early growth or metabolic phenotypes at age 31 years.Maturity onset diabetes of the young due to HNF1A variants in Croatia.Disparate genetic influences on polycystic ovary syndrome (PCOS) and type 2 diabetes revealed by a lack of association between common variants within the TCF7L2 gene and PCOS
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description
hulumtuese
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հետազոտող
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Amanda J Bennett
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Amanda J Bennett
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Amanda J Bennett
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Amanda J Bennett
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Amanda J Bennett
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Amanda J Bennett
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Amanda J Bennett
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Amanda J Bennett
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A J Bennett
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Amanda Bennett
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amanda bennett
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Amanda J Bennett
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Amanda J Bennett
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Amanda J Bennett
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Amanda J Bennett
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P106
P21
P31
P496
0000-0003-2140-8710