about
Ex vivo assays to study self-renewal, long-term expansion, and leukemic transformation of genetically modified human hematopoietic and patient-derived leukemic stem cells.Intrinsically disordered linker and plasma membrane-binding motif sort Ist2 and Ssy1 to junctions.BRD3/4 inhibition and FLT3-ligand deprivation target pathways that are essential for the survival of human MLL-AF9+ leukemic cells.Genetically engineered mesenchymal stromal cells produce IL-3 and TPO to further improve human scaffold-based xenograft models.Modeling BCR-ABL and MLL-AF9 leukemia in a human bone marrow-like scaffold-based xenograft model.Collagen density regulates the activity of tumor-infiltrating T cells
P50
description
researcher
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wetenschapper
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հետազոտող
@hy
name
Marco Carretta
@ast
Marco Carretta
@en
Marco Carretta
@es
Marco Carretta
@nl
type
label
Marco Carretta
@ast
Marco Carretta
@en
Marco Carretta
@es
Marco Carretta
@nl
prefLabel
Marco Carretta
@ast
Marco Carretta
@en
Marco Carretta
@es
Marco Carretta
@nl
P106
P31
P496
0000-0002-8135-7188