about
β2-glycoprotein I and protection from anti-SSA/Ro60-associated cardiac manifestations of neonatal lupus.A novel role of endothelin-1 in linking Toll-like receptor 7-mediated inflammation to fibrosis in congenital heart block.Targeting downstream transcription factors and epigenetic modifications following Toll-like receptor 7/8 ligation to forestall tissue injury in anti-Ro60 associated heart block.Ro60 requires Y3 RNA for cell surface exposure and inflammation associated with cardiac manifestations of neonatal lupusClonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization.IgD attenuates the IgM-induced anergy response in transitional and mature B cells.Ro52 autoantibodies arise from self-reactive progenitors in a mother of a child with neonatal lupus.Ro 60 functions as a receptor for beta(2)-glycoprotein I on apoptotic cells.Modulation of natural IgM autoantibodies to oxidative stress-related neo-epitopes on apoptotic cells in newborns of mothers with anti-Ro autoimmunity.Potentiation of a functional autoantibody in narcolepsy by a cholinesterase inhibitor.An autoantibody in narcolepsy disrupts colonic migrating motor complexes.A B cell apotope of Ro 60 in systemic lupus erythematosus.Molecular signature of a public clonotypic autoantibody in primary Sjögren's syndrome: a "forbidden" clone in systemic autoimmunity.IgV peptide mapping of native Ro60 autoantibody proteomes in primary Sjögren's syndrome reveals molecular markers of Ro/La diversification.Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination.B-cell receptor reconstruction from single-cell RNA-seq with VDJPuzzle.Reactivity with dichotomous determinants of Ro 60 stratifies autoantibody responses in lupus and primary Sjögren's syndromeDifferent temporal expression of immunodominant Ro60/60 kDa-SSA and La/SSB apotopesDifferential activation of complement by apoptotic cells opsonized with anti-Ro60 and anti-La autoantibodiesA Ro60 apotope is cryptic on the intracellular autoantigenAutoimmunity: Ro60-associated RNA takes its toll on disease pathogenesisMolecular Profiling and Clonal Tracking of Secreted Rheumatoid Factors in Primary Sjögren's SyndromeSequencing and Affinity Determination of Antigen-Specific B Lymphocytes from Peripheral BloodDNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation PatternsActivated PI3Kδ breaches multiple B cell tolerance checkpoints and causes autoantibody production
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description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Joanne H Reed
@ast
Joanne H Reed
@en
Joanne H Reed
@es
Joanne H Reed
@nl
type
label
Joanne H Reed
@ast
Joanne H Reed
@en
Joanne H Reed
@es
Joanne H Reed
@nl
prefLabel
Joanne H Reed
@ast
Joanne H Reed
@en
Joanne H Reed
@es
Joanne H Reed
@nl
P106
P31
P496
0000-0002-7585-7848