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The aging male hypothalamic-pituitary-gonadal axis: pulsatility and feedbackThe role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy menPulsatility of Hypothalamo-Pituitary Hormones: A Challenge in QuantificationRecent insights into neuroendocrine mechanisms of aging of the human male hypothalamic-pituitary-gonadal axis.Actions of estrogen on pulsatile, nyctohemeral, and entropic modes of growth hormone secretion.Time mode of growth hormone (GH) entry into the bloodstream and steady-state plasma GH concentrations, rather than sex, estradiol, or menstrual cycle stage, primarily determine the GH elimination rate in healthy young women and men.Disruption of the young-adult synchrony between luteinizing hormone release and oscillations in follicle-stimulating hormone, prolactin, and nocturnal penile tumescence (NPT) in healthy older men.Joint basal and pulsatile hypersecretory mechanisms drive the monotropic follicle-stimulating hormone (FSH) elevation in healthy older men: concurrent preservation of the orderliness of the FSH release process: a general clinical research center stuExpression of parathyroid hormone-related peptide (PTH-rp) and its receptorin the porcine ovary: regulation by transforming growth factor-beta and possible paracrine effects of granulosa cell PTH-rp secretion on theca cells.Mechanisms underlying the steroidogenic synergy of insulin and luteinizing hormone in porcine granulosa cells: joint amplification of pivotal sterol-regulatory genes encoding the low-density lipoprotein (LDL) receptor, steroidogenic acute regulatoryNature of altered pulsatile hormone release and neuroendocrine network signalling in human ageing: clinical studies of the somatotropic, gonadotropic, corticotropic and insulin axes.Older men manifest multifold synchrony disruption of reproductive neurohormone outflow.Luteinizing hormone (LH) drives diverse intracellular calcium second messenger signals in isolated porcine ovarian thecal cells: preferential recruitment of intracellular Ca2+ oscillatory cells by higher concentrations of LH.Calcium ions positively modulate follicle-stimulating hormone- and exogenous cyclic 3',5'-adenosine monophosphate-driven transcription of the P450(scc) gene in porcine granulosa cells.Gender and sexual maturation-dependent contrasts in the neuroregulation of growth hormone secretion in prepubertal and late adolescent males and females--a general clinical research center-based study.Longitudinal changes in growth hormone secretory process irregularity assessed transpubertally in healthy boys.Neuroendocrine control of pulsatile growth hormone release in the human: relationship with gender.Concerted regulation of steroidogenic acute regulatory gene expression by luteinizing hormone and insulin (or insulin-like growth factor I) in primary cultures of porcine granulosa-luteal cells.Recent neuroendocrine facets of male reproductive aging.Muting of androgen negative feedback unveils impoverished gonadotropin-releasing hormone/luteinizing hormone secretory reactivity in healthy older men.Continuous 24-hour intravenous infusion of recombinant human growth hormone (GH)-releasing hormone-(1-44)-amide augments pulsatile, entropic, and daily rhythmic GH secretion in postmenopausal women equally in the estrogen-withdrawn and estrogen-suppSecretory process regularity monitors neuroendocrine feedback and feedforward signaling strength in humans.Disruption of the joint synchrony of luteinizing hormone, testosterone, and androstenedione secretion in adolescents with polycystic ovarian syndrome.Developmentally delimited emergence of more orderly luteinizing hormone and testosterone secretion during late prepuberty in boys.Disruption of the synchronous secretion of leptin, LH, and ovarian androgens in nonobese adolescents with the polycystic ovarian syndrome.Neurophysiological regulation and target-tissue impact of the pulsatile mode of growth hormone secretion in the human.Corticotropin secretory dynamics in humans under low glucocorticoid feedback.Impact of pulsatility on the ensemble orderliness (approximate entropy) of neurohormone secretion.Putative activation of the peroxisome proliferator-activated receptor gamma impairs androgen and enhances progesterone biosynthesis in primary cultures of porcine theca cells.Unequal autonegative feedback by GH models the sexual dimorphism in GH secretory dynamics.Mechanisms of conjoint failure of the somatotropic and gonadal axes in ageing men.Hypophyseal-portal somatostatin (SRIH) and jugular venous growth hormone secretion in the conscious unrestrained ewe.Troglitazone, an insulin-sensitizing thiazolidinedione, represses combined stimulation by LH and insulin of de novo androgen biosynthesis by thecal cells in vitro.Gender governs the relationship between exercise intensity and growth hormone release in young adults.Interictal and postictal alterations of pulsatile secretions of luteinizing hormone in temporal lobe epilepsy in men.Accelerated escape from GH autonegative feedback in midpuberty in males: evidence for time-delimited GH-induced somatostatinergic outflow in adolescent boys.Pathophysiology of hyperinsulinemia following pancreas transplantation: altered pulsatile versus Basal insulin secretion and the role of specific transplant anatomy in dogs.Single and combined effects of growth hormone and testosterone administration on measures of body composition, physical performance, mood, sexual function, bone turnover, and muscle gene expression in healthy older men.Neuroendocrine facets of human puberty.Actions of endothelin-1 on swine ovarian (granulosa) cells.
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description
researcher
@en
wetenschapper
@nl
հետազոտող
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name
Johannes D Veldhuis
@ast
Johannes D Veldhuis
@en
Johannes D Veldhuis
@es
Johannes D Veldhuis
@nl
type
label
Johannes D Veldhuis
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Johannes D Veldhuis
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Johannes D Veldhuis
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Johannes D Veldhuis
@nl
prefLabel
Johannes D Veldhuis
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Johannes D Veldhuis
@en
Johannes D Veldhuis
@es
Johannes D Veldhuis
@nl
P106
P21
P31
P496
0000-0002-6477-7092