about
Structure of human cytidine deaminase bound to a potent inhibitorStructural insights into lesion recognition and repair by the bacterial 8-oxoguanine DNA glycosylase MutMDNA lesion recognition by the bacterial repair enzyme MutMStructural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylaseThe exomer cargo adaptor features a flexible hinge domain.DNA glycosylase recognition and catalysisData publication with the structural biology data grid supports live analysisBase excision repair.Distinct N-terminal regions of the exomer secretory vesicle cargo Chs3 regulate its trafficking itinerary.Cargo adaptors: structures illuminate mechanisms regulating vesicle biogenesis.Structural and mechanistic studies on repair of 8-oxoguanine in mammalian cells.Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments.The genetic basis of a craniofacial disease provides insight into COPII coat assembly.GTPase cross talk regulates TRAPPII activation of Rab11 homologues during vesicle biogenesisRegulation of vesicle trafficking: GTPases and friends.The Sec7 N-terminal regulatory domains facilitate membrane-proximal activation of the Arf1 GTPase.Biochemical methods for studying kinetic regulation of Arf1 activation by Sec7.Analysis of Arf1 GTPase-Dependent Membrane Binding and Remodeling Using the Exomer Secretory Vesicle Cargo Adaptor.The Sec7 Arf-GEF is recruited to the trans-Golgi network by positive feedback.Correction: The Sec7 N-terminal regulatory domains facilitate membrane-proximal activation of the Arf1 GTPase.Structural basis for membrane binding and remodeling by the exomer secretory vesicle cargo adaptor.Four GTPases differentially regulate the Sec7 Arf-GEF to direct traffic at the trans-golgi network.Capturing endosomal vesicles at the Golgi.The TRAPPIII complex activates the GTPase Ypt1 (Rab1) in the secretory pathway.Regulation of Arf activation occurs via distinct mechanisms at early and late Golgi compartments.A rapid and quantitative coat protein complex II vesicle formation assay using luciferase reporters.The HUS-box is required for allosteric regulation of the Sec7 Arf-GEF.Membrane trafficking: licensing a cargo receptor for ER exportNMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycleA Steric Gating Mechanism Dictates the Substrate Specificity of a Rab-GEF
P50
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P50
description
Forscher
@de
chercheur
@fr
investigador
@es
researcher
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ricercatore
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wetenschapper
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研究者
@zh
name
J Christopher Fromme
@ast
J Christopher Fromme
@en
J Christopher Fromme
@es
J Christopher Fromme
@nl
type
label
J Christopher Fromme
@ast
J Christopher Fromme
@en
J Christopher Fromme
@es
J Christopher Fromme
@nl
prefLabel
J Christopher Fromme
@ast
J Christopher Fromme
@en
J Christopher Fromme
@es
J Christopher Fromme
@nl
P106
P31
P4012
P496
0000-0002-8837-0473